Lupus

March 1997, Volume 6, Issue 3
Table of Contents

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Editorial

A Damage Index for Lupus Patients — Where are we now? 219
T Stoll, G Stucki, C Gordon & DA Isenberg
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Reviews

Behaviour of MRL Mice: An Animal Model of Disturbed Behaviour in Systemic Autoimmune Disease 223
H Szechtman, B S caronakic acute & JA Denburg
Abstract    Full Article (PDF)

Grand rounds from International lupus centres Clinico-Pathological Conference 230
SM Goodman, LR Sammaritano, EF DiCarlo, R Schneider & A Sanders
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Papers

Vasculitis in systemic lupus erythematosus 235
C Drenkard, AR Villa, E Reyes, M Abello & D Alarcón-Segovia
Abstract    Full Article (PDF)

Disease activity, cumulative damage and quality of life in systematic lupus erythematosus: results of a cross-sectional study 243
JG Hanly
Abstract    Full Article (PDF)

Systemic lupus erythematosus in Malaysia: a study of 539 patients and comparison of prevalence and disease expression in different racial and gender groups 248
F Wang, CL Wang, CT Tan & M Manivasagar
Abstract    Full Article (PDF)

Side-effects of intravenous cyclophosphamide pulse therapy 254
F Martin, B Lauwerys, C Lefèbvre, J-P Devogelaer & FA Houssiau
Abstract    Full Article (PDF)

Elevated serum levels of cyclo (His-Pro), an endogenous inhibitor of pituitary prolactin secretion, in systemic lupus erythematosus patients 258
LJ Jara, C Prasad & LR Espinoza
Abstract    Full Article (PDF)

Flow cytometric detection of circulating activated platelets in primary antiphospholipid syndrome. Correlation with thrombocytopenia and anticardiolipin antibodies 261
A Fanelli, C Bergamini, S Rapi, A Caldini, A Spinelli, A Buggiani & L Emmi
Abstract    Full Article (PDF)

Effect of cyclophosphamide on leukocytic infiltration in the brain of MRL/lpr mice 268
M Farrell, B Sakic acute, H Szechtman & JA Denburg
Abstract    Full Article (PDF)

Case Reports

Systemic lupus erythematosus with acanthosis nigricans, hyperpigmentation, and insulin receptor antibody 275
JS Baird, JL Johnson, D Elliott-Mills & LM Opas
Abstract    Full Article (PDF)

Churg-Strauss syndrome presented as multiple intracerebral hemorrhage 279
H-H Liou, H-M Liu, I-P Chiang, T-S Yeh & R-C Chen
Abstract    Full Article (PDF)

Congenital heart block and subsequent connective tissue disorder in adolescence 283
O Hubscher, D Carrillo & M Reichlin
Abstract    Full Article (PDF)

Letter to the Editor

Primary antiphospholipid syndrome evolving into systemic lupus erythematosus 285
L Seisdedos, FJ Muñoz-Rodríguez, R Cervera, J Font & M Ingelmo
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Manuscripts presented at the DNA Antibody Workshop held at the Middlesex Hospital, London on May 11-12 1996

Introduction 288
DA Isenberg & J Kalsi
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List of participants 289
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The role of antibodies to DNA in systemic lupus erythematosus–A review and introduction to an international workshop on DNA antibodies held in London, May 1996 290
DA Isenberg, CT Ravirajan, A Rahman & J Kalsi
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Clinical connections: assays and assessment 305
DA Bell & RJT Smeenk
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Are DNA antibodies actually pathogenic? 307
Y Naparstek & MP Madaio
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Genetic control of DNA antibody production: focus on the heavy chain 310
B Tsao & M Zouali
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DNA antibodies focus on the light chain 315
B Diamond & D Eilat
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Structural analysis of anti-DNA antibodies 317
JK Kalsi & B Sutton
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Expression of anti-DNA antibodies 321
FK Stevenson & GJ Silverman
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Environmental and other stimuli for DNA antibody production 324
J Kalden & TN Marion
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Characteristics of T cells that participate in the pathogenesis of SLE 330
BH Hahn & S Datta
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T helper cells driving pathogenic anti-DNA autoantibody production in lupus: nucleosomal epitopes and CD40 ligand signals 333
SK Datta, A Kaliyaperumal, C Mohan & Ami Desai-Mehta
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T and B cell recognition of idiotypes of anti-DNA autoantibodies 337
J Gavalchin & NA Staines
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Genetic and environmental issues in assessing the role of DNA antibodies–a summary of research presented at the DNA antibody workshop 344
RS Schwartz
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An overview of the anti-DNA antibody workshop: expansion of molecular structural analysis 346
BD Stollar
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T cells specific for DNA-binding peptides 349
M Wang, D Desai & TN Marion
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