Gene Therapy

November 1997, Volume 4, Issue 11
Table of Contents

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Editorial

Immuno gene therapy comes into its own 1129
M Sadelain & L Luzzatto
Full Article (PDF)

Paper

A novel herpesvirus amplicon system for in vivo gene delivery 1132
S Wang, S Di, W-B Young, C Jacobson & CJ Link Jr
Abstract    Full Article (PDF)

Adenovirus-mediated gene transfer during initial organogenesis in the mammalian embryo is promoter-dependent and tissue-specific 1142
HS Baldwin, C Mickanin & C Buck
Abstract    Full Article (PDF)

Retrovirus-mediated transfer of the human alphaL-iduronidase cDNA into human hematopoietic progenitor cells leads to correction in trans of Hurler fibroblasts 1150
M-M Huang, A Wong, X Yu, E Kakkis & DB Kohn
Abstract    Full Article (PDF)

Long-term survival of immunocompetent rats with intraperitoneal colon carcinoma tumors using herpes simplex thymidine kinase/ganciclovir and IL-2 treatments 1160
J-L Coll, M Mesnil, M-F Lefebvre, A Lancon & MC Favrot
Abstract    Full Article (PDF)

In vitro packaging of an infectious recombinant adeno-associated virus 2 1167
L Ding, S Lu & NC Munshi
Abstract    Full Article (PDF)

A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia 1173
A Fasbender, J Zabner, BG Zeiher & MJ Welsh
Abstract    Full Article (PDF)

Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFalpha 1181
RA Marr, CL Addison, D Snider, WJ Muller, J Gauldie & FL Graham
Abstract    Full Article (PDF)

HSV-1 thymidine kinase gene therapy for colorectal adenocarcinoma-derived peritoneal carcinomatosis 1189
C Lechanteur, F Princen, S Lo Bue, B Detroz, G Fillet, J Gielen, V Bours & M-P Merville
Abstract    Full Article (PDF)

Ability of a chimeric cAMP-responsive promoter to confer pharmacologic control of CFTR cDNA expression and cAMP-mediated Cl secretion 1195
M Suzuki, RN Singh & RG Crystal
Abstract    Full Article (PDF)

Gene therapy of diabetes: glucose-stimulated insulin secretion in a human hepatoma cell line (HEP G2ins/g) 1202
AM Simpson, GM Marshall, BE Tuch, L Maxwell, B Szymanska, J Tu, S Beynon, MA Swan & M Camacho
Abstract    Full Article (PDF)

Anti-HIV genetic treatment of antigen-specific human CD4 lymphocytes for adoptive immunotherapy of opportunistic infections in AIDS 1216
F Manca, D Fenoglio, E Franchin, D Saverino, G Li Pira, F Buffa, D Bignardi, L Del Pup & G Palù
Abstract    Full Article (PDF)

Integrin-mediated transfection with peptides containing arginine-glycine-aspartic acid domains 1225
SL Hart, L Collins, K Gustafsson & JW Fabre
Abstract    Full Article (PDF)

A second dose of a CFTR cDNA-liposome complex is as effective as the first dose in restoring cAMP-dependent chloride secretion to null CF mice trachea 1231
CA Goddard, R Ratcliff, JR Anderson, E Glenn, S Brown, DR Gill, SC Hyde, LJ MacVinish, L Huang, CF Higgins, AW Cuthbert, MJ Evans & WH Colledge
Abstract    Full Article (PDF)

Adenovirus-mediated transfer of a functional GAD gene into nerve cells: potential for the treatment of neurological diseases 1237
JJ Robert, V Bouilleret, V Ridoux, A Valin, MC Geoffroy, J Mallet & G Le Gal La Salle
Abstract    Full Article (PDF)

Local and systemic antitumor response after combined therapy of mouse metastatic tumors with tumor cells expressing IFN-alpha and HSVtk: perspectives for the generation of cancer vaccines 1246
L Santodonato, G D’Agostino, SM Santini, D Carlei, P Musiani, A Modesti, P Signorelli, F Belardelli & M Ferrantini
Abstract    Full Article (PDF)

Brief Communications

Rapid identification of viable retrovirus-transduced cells using the green fluorescent protein as a marker 1256
D Klein, S Indraccolo, K von Rombs, A Amadori, B Salmons & WH Günzburg
Abstract    Full Article (PDF)

Inhibition of HIV-1 replication by a Tat transdominant negative mutant in human peripheral blood lymphocytes from healthy donors and HIV-1-infected patients 1261
C Rossi, PG Balboni, M Betti, PC Marconi, R Bozzini, MP Grossi, G Barbanti-Brodano & A Caputo
Abstract    Full Article (PDF)

Foamy virus vectors for suicide gene therapy 1270
U Nestler, M Heinkelein, M Lücke, J Meixensberger, W Scheurlen, A Kretschmer & A Rethwilm
Abstract    Full Article (PDF)


© Macmillan Publishers Ltd 1998