British Journal of Pharmacology

27 November 1997, Volume 122, Issue 7
Table of Contents

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Papers

Cardiovascular effects of the novel Ca2+-sensitiser EMD 57033 in pigs at rest and during treadmill exercise 1257
René Stubenitsky, Rick W.P. van der Weerd, David B. Haitsma, Pieter D. Verdouw & Dirk J. Duncker
Abstract    Full Article (PDF)

Cardiovascular effects of CPU-23, a novel L-type calcium channel blocker with a unique molecular structure 1271
Hui Dong, Mary L. Earle, Yanfen Jiang, Kathy A. Loutzenhiser & Christopher R. Triggle
Abstract    Full Article (PDF)

ZM241385 is an antagonist of the facilitatory responses produced by the A2A adenosine receptor agonists CGS21680 and HENECA in the rat hippocampus 1279
Rodrigo A. Cunha, M. Dolores Constantino & J. Alexandre Ribeiro
Abstract    Full Article (PDF)

Electrophysiological basis for the antiarrhythmic action and positive inotropy of HA-7, a furoquinoline alkaloid derivative, in rat heart 1285
Ming-Jai Su, Gwo-Jyh Chang, Mei-Hwan Wu & Sheng-Chu Kuo
Abstract    Full Article (PDF)

Studies on the vasoconstrictor action of melatonin and putative melatonin receptor ligands in the tail artery of juvenile Wistar rats 1299
K.N. Ting, W.R. Dunn, D.J. Davies, D. Sugden, P. Delagrange, B. Guardiola-Lemaître, E. Scalbert & V.G. Wilson
Abstract    Full Article (PDF)

Further evidence for differences between cardiac atypical beta-adrenoceptors and brown adipose tissue beta3-adrenoceptors in the pithed rat 1307
Barbara Malinowska & Eberhard Schlicker
Abstract    Full Article (PDF)

Effect of mycophenolic acid on TNFalpha-induced expression of cell adhesion molecules in human venous endothelial cells in vitro 1315
Ingeborg A. Hauser, David R. Johnson, Frank Thévenod & Margarete Goppelt-Strübe
Abstract    Full Article (PDF)

Imaging of intracellular calcium during desensitization of nicotinic acetylcholine receptors of rat chromaffin cells 1323
L. Khiroug, R. Giniatullin, Elena Sokolova, Maria Talantova & A. Nistri
Abstract    Full Article (PDF)

Influence of flupirtine on a G-protein coupled inwardly rectifying potassium current in hippocampal neurones 1333
Regina Jakob & Josef Krieglstein
Abstract    Full Article (PDF)

Assessment of the role of alpha2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice 1339
J.C. Hunter, D.J. Fontana, L.R. Hedley, J.R. Jasper, R. Lewis, R.E. Link, R. Secchi, J. Sutton & R.M. Eglen
Abstract    Full Article (PDF)

Influence of interleukin 1alpha on superoxide anion, platelet activating factor release and phospholipase A2 activity of naive and sensitized guinea-pig alveolar macrophages 1345
Sabrina Mugnai, Mario Ciuffi, Manuela Maurizi, Daniela Bindi, Sergio Franchi-Micheli & Lucilla Zilletti
Abstract    Full Article (PDF)

Protective effect of darodipine, a calcium antagonist, on rat cardiomyocytes against oxygen radical-mediated injury 1353
Rosanna Matucci, Maria Francesca Ottaviani, Mario Barbieri, Elisabetta Cerbai & Alessandro Mugelli
Abstract    Full Article (PDF)

Recording of the saphenous vein compliance by an ultrasonic echo-tracking device in the dog: effects of S 18149 1361
Christine Vayssettes-Courchay, Alex A. Cordi, Jean-Michel Lacoste, Michel Laubie & Tony J. Verbeuren
Abstract    Full Article (PDF)

Acute non-insulin-like stimulation of rat muscle glucose metabolism by troglitazone in vitro 1367
C. Fürnsinn, S. Neschen, C. Noe, M. Bisschop, M. Roden, C. Vogl, B. Schneider & W. Waldhäusl
Abstract    Full Article (PDF)

Noradrenaline, beta-adrenoceptor mediated vasorelaxation and nitric oxide in large and small pulmonary arteries of the rat 1375
R.M. Priest, D. Hucks & J.P.T. Ward
Abstract    Full Article (PDF)

Investigation of the inhibitory effect of NG-nitro-L-arginine methyl ester on the antihypertensive effect of the angiotensin AT1 receptor antagonist, GR138950 1385
Ian K. Anderson & Geoffrey M. Drew
Abstract    Full Article (PDF)

Inhibitory effects of genistein on ATP-sensitive K+ channels in rabbit portal vein smooth muscle 1395
Rika Ogata, Kenji Kitamura, Yushi Ito & Hitoo Nakano
Abstract    Full Article (PDF)

Increased feeding in fatty Zucker rats by the thiazolidinedione BRL 49653 (rosiglitazone) and the possible involvement of leptin and hypothalamic neuropeptide Y 1405
Qiong Wang, Simon Dryden, Helen M. Frankish, Chen Bing, Lucy Pickavance, David Hopkins, Robin Buckingham & Gareth Williams
Abstract    Full Article (PDF)

Age-related changes in purinergic and adrenergic components of sympathetic neurotransmission in guinea-pig seminal vesicles 1411
Christian Pinna, Annalisa Rubino & Geoffrey Burnstock
Abstract    Full Article (PDF)

Effect of fluoxetine on a neuronal, voltage-dependent potassium channel (Kv1.1) 1417
J. Tytgat, Ch. Maertens & P. Daenens
Abstract    Full Article (PDF)

Cyclic GMP-dependent protein kinase activation in the absence of negative inotropic effects in the rat ventricle 1425
Karen L. MacDonell & Jack Diamond
Abstract    Full Article (PDF)

Effects of a nonpeptide bradykinin B2 receptor antagonist, FR167344, on different in vivo animal models of inflammation 1436
Masayuki Asano, Chie Hatori, Noriaki Inamura, Hiroe Sawai, Jiro Hirosumi, Tatsujiro Fujiwara & Kunio Nakahara
Abstract    Full Article (PDF)

Ruthenium complexes as nitric oxide scavengers: a potential therapeutic approach to nitric oxide-mediated diseases 1441
S.P. Fricker, Elizabeth Slade, N.A. Powell, O.J. Vaughan, G.R. Henderson, B.A. Murrer, I.L. Megson, S.K. Bisland & F.W. Flitney
Abstract    Full Article (PDF)

Human vascular kinin receptors of the B2 type characterized by radioligand binding 1450
S. Gessi, A. Rizzi, G. Calò, G. Agnello, G. Jorizzo, G. Mollica, P.A. Borea & D. Regoli
Abstract    Full Article (PDF)

Characterization of 5-HT receptors on human pulmonary artery and vein: functional and binding studies 1455
Julio Cortijo, Miguel Martí-Cabrera, Eva Bernabeu, Teresa Domènech, Josep Bou, Andrés G. Fernández, Jorge Beleta, José M. Palacios & Esteban J. Morcillo
Abstract    Full Article (PDF)

Glucose-lowering effect of BTS 67 582 1464
T. Page & C.J. Bailey
Abstract    Full Article (PDF)

Evidence of an important and direct role for protein kinase C in agonist-induced phosphorylation leading to desensitization of the angiotensin AT1A receptor 1469
A.J. Balmforth, F.H. Shepherd, P. Warburton & S.G. Ball
Abstract    Full Article (PDF)

Spinal pharmacology of tactile allodynia in diabetic rats 1478
Nigel A. Calcutt & Sandra R. Chaplan
Abstract    Full Article (PDF)

Lipopolysaccharide induces expression of tumour necrosis factor alpha in rat brain: inhibition by methylprednisolone and by rolipram 1483
M. Buttini, A. Mir, K. Appel, K.H. Wiederhold, S. Limonta, P.J. Gebicke-Haerter & H.W.G.M. Boddeke
Abstract    Full Article (PDF)

The effect of losigamone (AO-33) on electrical activity and excitatory amino acid release in mouse cortical slices 1490
Jayashri Srinivasan, Alan Richens & John A. Davies
Abstract    Full Article (PDF)

AT2-antagonist sensitive potentiation of angiotensin II-induced vasoconstrictions by blockade of nitric oxide synthesis in rat renal vasculature 1495
Catherine Muller, Karlhans Endlich, Mariette Barthelmebs & Jean-Jacques Helwig
Abstract    Full Article (PDF)

Dobesilate enhances endothelial nitric oxide synthase-activity in macro- and microvascular endothelial cells 1502
Christoph Suschek, Hubert Kolb & Victoria Kolb-Bachofen
Abstract    Full Article (PDF)

Activation of two sites by adenosine receptor agonists to cause relaxation in rat isolated mesenteric artery 1509
D.J. Prentice, S.L. Payne & S.M.O. Hourani
Abstract    Full Article (PDF)

The regulation of mitogenesis and apoptosis in response to the persistent stimulation of alpha1-adrenoceptors: a possible role of 15-lipoxygenase 1516
Eisuke Nishio & Yasuhiro Watanabe
Abstract    Full Article (PDF)

Activation of soluble guanylyl cyclase by YC-1 in aortic smooth muscle but not in ventricular myocardium from rat 1523
Jörg W. Wegener, Ingolf Gath, Ulrich Förstermann & Hermann Nawrath
Abstract    Full Article (PDF)

Neuropeptide Y (NPY) and peptide YY (PYY) effects in the epididymis of the guinea-pig: evidence of a pre-junctional PYY-selective receptor 1530
John M. Haynes, Stephen J. Hill & Lisa A. Selbie
Abstract    Full Article (PDF)


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