Leukemia

February 1997, Volume 11, Issue 2
Table of Contents

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Pharmacological Review

Pharmacological approach for optimization of the dose schedule of 5-Aza-2’-deoxycytidine (Decitabine) for the therapy of leukemia 175
RL Momparler, S Côté & N Eliopoulos
Abstract    Full Article (PDF)

Minireview

SHIP, a new player in cytokine-induced signalling 181
L Liu, JE Damen, M Ware, M Hughes & G Krystal
Abstract    Full Article (PDF)

Therapy And Therapeutic Intervention

High-dose cytosine arabinoside and etoposide: an effective regimen without anthracyclines for refractory childhood acute non-lymphocytic leukemia 185
JA Whitlock, RJ Wells, JD Hord, RL Janco, JP Greer, JC Gay, JR Edwards, TL McCurley & JN Lukens
Abstract    Full Article (PDF)

Chronic Myeloid Leukemia

Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression 190
K Ohyashiki, JH Ohyashiki, H Iwama, S Hayashi, JW Shay & K Toyama
Abstract    Full Article (PDF)

Clonal instability preceding lymphoid blastic transformation of chronic myeloid leukemia 195
A Spencer, T Vulliamy, J Kaeda, JM Goldman & JV Melo
Abstract    Full Article (PDF)

Acute Myeloid Leukemia

Clonality analysis of hematopoietic cell lineages in acute myeloid leukemia and translocation (8;21): only myeloid cells are part of the malignant clone 202
K van Lom, A Hagemeijer, F Vandekerckhove, GE de Greef, N Sacchi & B Löwenberg
Abstract    Full Article (PDF)

Myelodysplasia

Myelodysplastic syndrome in children: differentiation from acute myeloid leukemia with a low blast count 206
GCF Chan, WC Wang, SC Raimondi, FG Behm, RA Krance, G Chen, A Freiberg, L Ingram, D Butler & DR Head
Abstract    Full Article (PDF)

Cell Biology Of Retinoids

Expression of the Zn finger gene, EVI-1, in acute promyelocytic leukemia 212
ZF Xi, M Russell, S Woodward, F Thompson, L Wagner & R Taetle
Abstract    Full Article (PDF)

Potentiation of VD-induced monocytic leukemia cell differentiation by retinoids involves both RAR and RXR signaling pathways 221
H Defacque, C Sévilla, D Piquemal, C Rochette-Egly, J Marti & T Commes
Abstract    Full Article (PDF)

Molecular Cytogenetics

Delineation of a 6 cM commonly deleted region in childhood acute lymphoblastic leukemia on the 6q chromosomal arm 228
B Gérard, H Cavé, C Guidal, N Dastugue, E Vilmer & B Grandchamp
Abstract    Full Article (PDF)

The commonly deleted region at 9p21-22 in lymphoblastic leukemias spans at least 400 kb and includes p16 but not p15 or the IFN gene cluster 233
RCT Aguiar, H Sill, JM Goldman & NCP Cross
Abstract    Full Article (PDF)

Growth Factors And Cytokines

A fraction unresponsive to growth inhibition by TGF-beta among the high-proliferative potential progenitor cells in bone marrow of p53-deficient mice 239
H Sasaki, M Matsuda, Y Lu, K Ikuta, S Matsuyama, Y Hirabayashi, H Mitsui, T Matsumura, M Muramatsu, T Tsukada, S Aizawa & T Inoue
Abstract    Full Article (PDF)

Autocrine IL-2-dependent growth of a newly established CD3+, CD16, CD56+, CD57+, JH, TCRbeta, TCRgamma leukemia cell line (NOI-90) 245
Y Sahraoui, M Perraki, M Theodoropoulou, M Allouche, A Tsapis, A Ammar, C Clemenceau, S Bokogiorgou, T Yacci, G Katrinakis, C Jasmin & V Georgoulias
Abstract    Full Article (PDF)

Sensitivity And Resistance To Therapy

Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells 253
Y Huang, AM Ibrado, JC Reed, G Bullock, S Ray, C Tang & K Bhalla
Abstract    Full Article (PDF)

Apoptosis

Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis 258
A König, T Menzel, S Lynen, L Wrazel, A Rosén, A Al-Katib, E Raveche & JL Gabrilove
Abstract    Full Article (PDF)

Virology

Human herpes virus 8 (Kaposi’s sarcoma herpes virus) and malignant lymphoproliferations in France: a molecular study of 250 cases including two AIDS-associated body cavity based lymphomas 266
A Gessain, J Brière, C Angelin-Duclos, F Valensi, H Merle Béral, F Davi, M-A Nicola, A Sudaka, N Fouchard, J Gabarre, X Troussard, E Dulmet, J Audouin, J Diebold & G de Thé
Abstract    Full Article (PDF)

Differentiation

NF-E2p18/mafK is required in DMSO-induced differentiation of Friend erythroleukemia cells by enhancing NF-E2 activity 273
C Francastel, V Poindessous-Jazat, Y Augery-Bourget & J Robert-Lézénès
Abstract    Full Article (PDF)

Myeloma

Adoptive immunotherapy for relapsed multiple myeloma after allogeneic bone marrow transplantation (BMT): evidence for a graft-versus-myeloma effect 281
H Bertz, JA Burger, R Kunzmann, R Mertelsmann & J Finke
Abstract    Full Article (PDF)

Establishment and characterization of a human stroma-dependent myeloma cell line (MM5.1) and its stroma-independent variant (MM5.2) 284
I Van Riet, C De Greef, F Aharchi, C Woischwill, M De Waele, M Bakkus, P Lacor, R Schots & B Van Camp
Abstract    Full Article (PDF)

Brief Communications

Good correlation between RT-PCR analysis and relapse in Philadelphia (Ph1)-positive acute lymphoblastic leukemia (ALL) 294
C Preudhomme, N Henic, B Cazin, JL Laï, MF Bertheas, M Vanrumbeke, F Lemoine, JP Jouet, E Deconninck, B Nelken, A Cosson & P Fenaux
Abstract    Full Article (PDF)

Loss of the DEK-CAN fusion transcript in a child with t(6;9) acute myeloid leukemia following chemotherapy and allogeneic bone marrow transplantation 299
J Boer, H Mahmoud, S Raimondi, G Grosveld & R Krance
Full Article (PDF)

Bio-Technical Section Bts

Molecular analysis of hematopoietic colonies derived from chronic myeloid leukemia patients: interphase fluorescence in situ hybridization compared with RT-PCR 301
SFT Thijsen, GJ Schuurhuis, JW van Oostveen, AP Theijsmeijer, MMAC Langenhuijsen & GJ Ossenkoppele
Abstract    Full Article (PDF)

Correspondence, Case Report

Evidence for the embryonic origin of partial chromosome 7 deletion in monozygotic twins with juvenile chronic myelogenous leukemia 306
V Najfeld, A Vlachos, R Parker, W Burnett, A Scalise & S Fruchtman
Abstract    Full Article (PDF)

Letter to the Editor

Concentrations of serum leukemia inhibitory factor (LIF) in patients with hematologic malignances 311
V Lorgeot, V Praloran, P Turlure & Y Denizot
Full Article (PDF)


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