Gene Therapy

December 1997, Volume 4, Issue 12
Table of Contents

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News and Comments 1279
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Editorial

Hybrid vectors: a new generation of virus-based vectors designed to control the cellular fate of delivered genes 1281
D Jacoby, C Fraefel & XO Breakefield
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Review

Gene therapy strategies for AIDS-related malignancies 1284
TJ Curiel, A Piché, K Kasono & DT Curiel
Abstract    Full Article (PDF)

Papers

Antisense raf oligodeoxyribonucleotide is protected by liposomal encapsulation and inhibits Raf-1 protein expression in vitro and in vivo: implication for gene therapy of radioresistant cancer 1289
PC Gokhale, V Soldatenkov, F-H Wang, A Rahman, A Dritschilo & U Kasid
Abstract    Full Article (PDF)

Intracerebral recombinant HSV-1 vector does not reactivate latent HSV-1 1300
Q Wang, J Guo & W Jia
Abstract    Full Article (PDF)

Complementation of the genetic defect in Gunn rat hepatocytes in vitro by highly efficient gene transfer with cationic liposomes 1305
M Wilke, A Bijma, AJT Timmers-Reker, BJ Scholte & M Sinaasappel
Abstract    Full Article (PDF)

On the mechanism of DNA transfection: efficient gene transfer without viruses 1313
A Coonrod, F-Q Li & M Horwitz
Abstract    Full Article (PDF)

Characterization of the antitumor immune response generated by treatment of murine tumors with recombinant adenoviruses expressing HSVtk, IL-2, IL-6 or B7-1 1322
T Felzmann, WJ Ramsey & RM Blaese
Abstract    Full Article (PDF)

Development of replicative and nonreplicative hepatitis B virus vectors 1330
S Chaisomchit, DLJ Tyrrell & L-J Chang
Abstract    Full Article (PDF)

A new DNA vehicle for nonviral gene delivery: supercoiled minicircle 1341
A-M Darquet, B Cameron, P Wils, D Scherman & J Crouzet
Abstract    Full Article (PDF)

In vitro immune modulation by antibodies coupled to tumour cells 1350
D Darling, J Galea-Lauri, J Gäken, P Towner, M Kuiper, S Hollingsworth, W Hirst, A Barnard, A Buggins, G Mufti & F Farzaneh
Abstract    Full Article (PDF)

Multicomponent gene therapy vaccines for lung cancer: effective eradication of established murine tumors in vivo with interleukin-7/herpes simplex thymidine kinase-transduced autologous tumor and ex vivo activated dendritic cells 1361
S Sharma, PW Miller, M Stolina, L Zhu, M Huang, RW Paul & SM Dubinett
Abstract    Full Article (PDF)

Expression of exogenous wt-p53 does not affect normal hematopoiesis: implications for bone marrow purging 1371
R Scardigli, G Bossi, G Blandino, M Crescenzi, S Soddu & A Sacchi
Abstract    Full Article (PDF)

Brief Communications

The effect of cationic liposome pretreatment and centrifugation on retrovirus-mediated gene transfer 1379
WP Swaney, FL Sorgi, AB Bahnson & JA Barranger
Abstract    Full Article (PDF)

Use of a novel cross-linking method to modify adenovirus tropism 1387
BE Rogers, JT Douglas, C Ahlem, DJ Buchsbaum, J Frincke & DT Curiel
Abstract    Full Article (PDF)

Development of safe and efficient retroviral vectors for Gaucher disease 1393
M Havenga, R Fisher, P Hoogerbrugge, B Roberts, D Valerio & HHG van Es
Abstract    Full Article (PDF)

Author Index 1401
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Keyword Index 1405
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