Gene Therapy

February 1997, Volume 4, Issue 2
Table of Contents

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News and Comments

77

Editorial

Nitroreductase activation of DB1954 – an alternative ‘suicide’ gene system 80
SM Bailey & IR Hart
Full Article (PDF)

Papers

Suitability of Epstein-Barr virus-based episomal vectors for expression of cytokine genes in human lymphoma cells 82
S Mücke, A Polack, M Pawlita, D Zehnpfennig, N Massoudi, H Bohlen, W Doerfler, G Bornkamm, V Diehl & J Wolf
Abstract    Full Article (PDF)

The expression of bacterial nitroreductase in transgenic mice results in specific cell killing by the prodrug CB1954 93
D Drabek, J Guy, R Craig & F Grosveld
Abstract    Full Article (PDF)

Selective cell ablation in transgenic mice expressing E. coli nitroreductase 101
AJ Clark, M Iwobi, W Cui, M Crompton, G Harold, S Hobbs, T Kamalati, R Knox, C Neil, F Yull & B Gusterson
Abstract    Full Article (PDF)

Gene transfer to the central nervous system by transplantation of cerebral endothelial cells 111
J Quinonéro, J-L Tchélingérian, L Vignais, N Foignant-Chaverot, C Colin, P Horellou, R Liblau, G Barbin, AD Strosberg, C Jacque & P-O Couraud
Abstract    Full Article (PDF)

Survival of grafts of genetically modified cardiac myocytes transfected with FITC-labeled oligodeoxynucleotides and the beta-galactosidase gene in the noninfarcted area, but not the myocardial infarcted area 120
M Aoki, R Morishita, J Higaki, A Moriguchi, S Hayashi, H Matsushita, I Kida, N Tomita, Y Sawa, Y Kaneda & T Ogihara
Abstract    Full Article (PDF)

High transdominant RevM10 protein levels are required to inhibit HIV-1 replication in cell lines and primary T cells: implication for gene therapy of AIDS 128
I Plavec, M Agarwal, KE Ho, M Pineda, J Auten, J Baker, H Matsuzaki, S Escaich, M Bonyhadi & E Böhnlein
Abstract    Full Article (PDF)

Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia 140
Z Xing, Y Ohkawara, M Jordana, FL Graham & J Gauldie
Abstract    Full Article (PDF)

A simple procedure to determine the biological titer of recombinant retroviral vectors 150
N Tavoloni
Abstract    Full Article (PDF)

In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer 156
J-L Coll, E Wagner, V Combaret, K Metchler, H Amstutz, I Iacono-Di-Cacito, N Simon & MC Favrot
Abstract    Full Article (PDF)

High efficiency reporter gene transfection of vascular tissue in vitro and in vivo using a cationic lipid-DNA complex 162
M-C Keogh, D Chen, F Lupu, N Shaper, JF Schmitt, VV Kakkar & NR Lemoine
Abstract    Full Article (PDF)

Brief Communication

Optimized conditions for the production of recombinant amphotropic retroviral vector preparations 172
LCM Kaptein, AE Greijer, D Valerio & VW van Beusechem
Abstract    Full Article (PDF)


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