Gene Therapy

March 1997, Volume 4, Issue 3
Table of Contents

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News & Comments

177

Editorial

Combined strategies for gene therapy of AIDS 179
Giorgio Palù
Full Article (PDF)

Papers

Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA 181
HL Davis, CL Brazolot Millan & SC Watkins
Abstract    Full Article (PDF)

Improved efficiency of arterial gene transfer by use of poloxamer 407 as a vehicle for adenoviral vectors 189
LJ Feldman, CJ Pastore, N Aubailly, M Kearney, D Chen, M Perricaudet, PG Steg & JM Isner
Abstract    Full Article (PDF)

A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis 199
DR Gill, KW Southern, KA Mofford, T Seddon, L Huang, F Sorgi, A Thomson, LJ MacVinish, R Ratcliff, D Bilton, DJ Lane, JM Littlewood, AK Webb, PG Middleton, WH Colledge, AW Cuthbert, MJ Evans, CF Higgins & SC Hyde
Abstract    Full Article (PDF)

Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis 210
DJ Porteous, JR Dorin, G McLachlan, H Davidson-Smith, H Davidson, BJ Stevenson, AD Carothers, WAH Wallace, S Moralee, C Hoenes, G Kallmeyer, U Michaelis, K Naujoks, L-P Ho, JM Samways, M Imrie, AP Greening & JA Innes
Abstract    Full Article (PDF)

Use of SV40-based vectors to transduce foreign genes to normal human peripheral blood mononuclear cells 219
DS Strayer, R Kondo, J Milano & L-X Duan
Abstract    Full Article (PDF)

Characterization of liposome-mediated gene delivery: expression, stability and pharmacokinetics of plasmid DNA 226
AR Thierry, P Rabinovich, B Peng, LC Mahan, JL Bryant & RC Gallo
Abstract    Full Article (PDF)

Safety studies of the intraperitoneal injection of E1A-liposome complex in mice 238
X Xing, V Liu, W Xia, LC Stephens, L Huang, G Lopez-Berestein & M-C Hung
Abstract    Full Article (PDF)

Mechanism of ‘bystander effect’ killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment 244
H Ishii-Morita, R Agbaria, CA Mullen, H Hirano, DA Koeplin, Z Ram, EH Oldfield, DG Johns & RM Blaese
Abstract    Full Article (PDF)

Constitutive systemic expression of IL-1Ra or soluble TNF receptor by genetically modified hematopoietic cells suppresses LPS induction of IL-6 and IL-10 252
LA Doughty, KD Patrene, CH Evans, SS Boggs & PD Robbins
Abstract    Full Article (PDF)

Isolation and characterization of packaging cell lines that coexpress the adenovirus E1, DNA polymerase, and preterminal proteins: implications for gene therapy 258
A Amalfitano & JS Chamberlain
Abstract    Full Article (PDF)

Brief Communications

A strategy for specific targeting of therapeutic agents to tumour cells of virus-associated cancers 264
TJ Evans, L Brooks & PJ Farrell
Abstract    Full Article (PDF)

Human CD34+ cells do not express glutathione S-transferases alpha 268
M Czerwinski, H-P Kiem & JT Slattery
Abstract    Full Article (PDF)


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