Gene Therapy

July 1998, Volume 5, Issue 7
Table of Contents

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News and Comments

GT News 861
Full Article (PDF)

Editorial

Immunological approach to gene therapy of human cancer: improvements through the understanding of mechanism(s) 863
G Parmiani
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Papers

Humoral and cellular immune responses of dogs immunized with a nucleic acid vaccine encoding human carcinoembryonic antigen 865
BF Smith, HJ Baker, DT Curiel, W Jiang & RM Conry
Abstract    Full Article (PDF)

Rapid adenoviral transduction of freshly resected tumour explants with therapeutically useful genes provides a rationale for genetic immunotherapy for colorectal cancer 869
RM Diaz, S Todryk, H Chong, IR Hart, K Sikora, S Dorudi & RG Vile
Abstract    Full Article (PDF)

Uncoupling of 2-fluoro-2-deoxyglucose transport and phosphorylation in rat hepatoma during gene therapy with HSV thymidine kinase 880
U Haberkorn, ME Bellemann, L Gerlach, I Morr, H Trojan, G Brix, A Altmann, J Doll & G van Kaick
Abstract    Full Article (PDF)

Regulatable production of insulin from primary-cultured hepatocytes: insulin production is up-regulated by glucagon and cAMP and down-regulated by insulin 888
D Lu, H Tamemoto, H Shibata, I Saito & T Takeuchi
Abstract    Full Article (PDF)

Enhanced in vivo adenovirus-mediated gene transfer to rat hepatocarcinomas by selective administration into the hepatic artery 896
R Gérolami, J Cardoso, M-P Bralet, C-A Cuenod, O Clément, P-L Tran & C Bréchot
Abstract    Full Article (PDF)

Transcriptional activation of NF-B activity by Epstein-Barr virus (EBV) LMP1 as a selective therapeutic strategy for EBV-associated diseases 905
CJ Wu, CY Leu, ST Liu, KP Chow, CL Meng & YS Chang
Abstract    Full Article (PDF)

Optimised retroviral infection of human epidermal keratinocytes: long-term expression of transduced integrin gene following grafting on to SCID mice 913
L Levy, S Broad, AJ Zhu, JM Carroll, I Khazaal, B Péault & FM Watt
Abstract    Full Article (PDF)

Apoptosis-mediated regulation of recombinant human granulocyte colony-stimulating factor production by genetically engineered fibroblasts 923
M Kokubun, A Kume, M Urabe, H Mano, M Okubo, R Kasukawa, A Kakizuka & K Ozawa
Abstract    Full Article (PDF)

Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery 930
S Li, MA Rizzo, S Bhattacharya & L Huang
Abstract    Full Article (PDF)

Adeno-associated virus vectors can be efficiently produced without helper virus 938
T Matsushita, S Elliger, C Elliger, G Podsakoff, L Villarreal, GJ Kurtzman, Y Iwaki & P Colosi
Abstract    Full Article (PDF)

Inhibition of Tat-mediated transactivation and HIV replication with Tat mutant and repressor domain fusion proteins 946
C Fraisier, DA Abraham, M van Oijen, V Cunliffe, A Irvine, R Craig & EA Dzierzak
Abstract    Full Article (PDF)

Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides 955
S Simões, V Slepushkin, R Gaspar, MC Pedroso de Lima & N Düzgünescedil
Abstract    Full Article (PDF)

Adenoviral delivery of B7-1 (CD80) increases the immunogenicity of human ovarian and cervical carcinoma cells 965
MG Gilligan, P Knox, S Weedon, R Barton, DJ Kerr, P Searle & LS Young
Abstract    Full Article (PDF)

Adenovirus-mediated expression of melanoma antigen gp75 as immunotherapy for metastatic melanoma 975
EA Hirschowitz, S Leonard, W Song, B Ferris, PL Leopold, JJ Lewis, WB Bowne, S Wang, AN Houghton & RG Crystal
Abstract    Full Article (PDF)

Genetic co-inactivation of macrophage- and T-tropic HIV-1 chemokine coreceptors CCR-5 and CXCR-4 by intrakines 984
X Bai, J-D Chen, A-G Yang, F Torti & S-Y Chen
Abstract    Full Article (PDF)

Adenovirus complexed with polyethylene glycol and cationic lipid is shielded from neutralizing antibodies in vitro 995
M Chillón, JH Lee, A Fasbender & MJ Welsh
Abstract    Full Article (PDF)

Brief Communication

Production and characterization of a bicistronic Moloney-based retroviral vector expressing human interleukin 2 and herpes simplex virus thymidine kinase for gene therapy of cancer 1003
M Pizzato, E Franchin, P Calvi, R Boschetto, M Colombo, S Ferrini & G Palù
Abstract    Full Article (PDF)


© Macmillan Publishers Ltd 1998