Gene Therapy

August 1998, Volume 5, Issue 8
Table of Contents

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News and Comments

GT News 1009
Full Article (PDF)

Meeting Perspective

American Society for Gene Therapy 1st Annual Meeting 1010
L-A Martin & HS Pandha
Full Article (PDF)

Editorial

Targeting angiogenesis: genetic intervention which strikes at the weak link of tumorigenesis 1011
T Taniguchi, A Rigg & NR Lemoine
Full Article (PDF)

Papers

Continuous delivery of human and mouse erythropoietin in mice by genetically engineered polymer encapsulated myoblasts 1014
E Régulier, BL Schneider, N Déglon, Y Beuzard & P Aebischer
Abstract    Full Article (PDF)

Pre-treatment with elastase improves the efficiency of percutaneous adenovirus-mediated gene transfer to the arterial media 1023
L Maillard, M Ziol, O Tahlil, C Le Feuvre, LJ Feldman, D Branellec, P Bruneval & PhG Steg
Abstract    Full Article (PDF)

Sustained transgene expression in vitro and in vivo using an Epstein-Barr virus replicon vector system combined with HVJ liposomes 1031
Y Saeki, M Wataya-Kaneda, K Tanaka & Y Kaneda
Abstract    Full Article (PDF)

Immune responses limit adenovirally mediated gene expression in the adult mouse eye 1038
MB Reichel, RR Ali, AJ Thrasher, DM Hunt, SS Bhattacharya & D Baker
Abstract    Full Article (PDF)

Efficient Fas-ligand gene expression in rodent liver after intravenous injection of a recombinant adenovirus by the use of a Cre-mediated switching system 1047
T Okuyama, M Fujino, X-K Li, N Funeshima, M Kosuga, I Saito, S Suzuki & M Yamada
Abstract    Full Article (PDF)

Repeated cycles of retrovirus-mediated HSVtk gene transfer plus ganciclovir increase survival of rats with peritoneal carcinomatosis 1054
F Princen, C Lechanteur, M Lopez, G Rocoux, B Detroz, J Gielen, G Fillet, M-P Merville & V Bours
Abstract    Full Article (PDF)

Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954 1061
IA McNeish, NK Green, MG Gilligan, MJ Ford, V Mautner, LS Young, DJ Kerr & PF Searle
Abstract    Full Article (PDF)

Targeted chemotherapy by intratumour injection of encapsulated cells engineered to produce CYP2B1, an ifosfamide activating cytochrome P450 1070
M Löhr, P Müller, P Karle, J Stange, S Mitzner, R Jesnowski, H Nizze, B Nebe, S Liebe, B Salmons & WH Günzburg
Abstract    Full Article (PDF)

Lipid-mediated gene transfer of viral IL-10 prolongs vascularized cardiac allograft survival by inhibiting donor-specific cellular and humoral immune responses 1079
LA DeBruyne, K Li, SY Chan, L Qin, DK Bishop & JS Bromberg
Abstract    Full Article (PDF)

A vitrectomy improves the transfection efficiency of adenoviral vector-mediated gene transfer to Müller cells 1088
T Sakamoto, H Ueno, Y Goto, Y Oshima, T Ishibashi & H Inomata
Abstract    Full Article (PDF)

Expression of human bone morphogenic protein 7 in primary rabbit periosteal cells: potential utility in gene therapy for osteochondral repair 1098
JM Mason, DA Grande, M Barcia, R Grant, RG Pergolizzi & AS Breitbart
Abstract    Full Article (PDF)

Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice 1105
H Li, H Lu, F Griscelli, P Opolon, L-Q Sun, T Ragot, Y Legrand, D Belin, J Soria, C Soria, M Perricaudet & P Yeh
Abstract    Full Article (PDF)

Actions of HSVtk and connexin43 gene delivery on gap junctional communication and drug sensitization in hepatocellular carcinoma 1114
AM Ghoumari, R Mouawad, A Zerrouqi, C Nizard, N Provost, D Khayat, CCG Naus & Cl Soubrane
Abstract    Full Article (PDF)

Intracerebral injection of adenovirus harboring the HSVtk gene combined with ganciclovir administration: toxicity study in nonhuman primates 1122
MJ Driesse, AJPE Vincent, PAE Sillevis Smitt, JM Kros, PM Hoogerbrugge, CJJ Avezaat, D Valerio & A Bout
Abstract    Full Article (PDF)

Adenovirus-mediated GM-CSF gene and cytosine deaminase gene transfer followed by 5-fluorocytosine administration elicit more potent antitumor response in tumor-bearing mice 1130
X Cao, DW Ju, Q Tao, J Wang, T Wan, BM Wang, W Zhang & H Hamada
Abstract    Full Article (PDF)

High efficiency gene transfer to the central nervous system of rodents and primates using herpes virus vectors lacking functional ICP27 and ICP34.5 1137
MK Howard, T Kershaw, B Gibb, N Storey, AR MacLean, B-Y Zeng, BC Tel, P Jenner, SM Brown, CJ Woolf, PN Anderson, RS Coffin & DS Latchman
Abstract    Full Article (PDF)

Brief Communication

High throughput method for creating and screening recombinant adenoviruses 1148
AR Davis, K Meyers & JM Wilson
Abstract    Full Article (PDF)


© Macmillan Publishers Ltd 1998