March 1997, Volume 3, Issue 1, Pages 3 – 8

Invited Editorial

Chemokines and chemokine receptors: the key to understanding AIDS MH Thornhill & J Li Oral Disease Research Centre, University Dental Hospital of Manchester, Manchester, UK

Keywords

chemokines;   receptors;   HIV;   AIDS;   review

Abstract

This article reviews the recent rapid developments in research that have demonstrated the importance of chemokines and their receptors in HIV infection and the progression to AIDS. These discoveries have transformed our understanding of how the virus may infect cells and why certain individuals may be resistant to HIV infection, and for the first time have opened up the very real prospect of developing strategies to prevent and treat this disease.

Received 15 January 1997; Accepted 31 January 1997

^© Macmillan Publishers Ltd 1997