British Journal of Pharmacology

13 November 1997, Volume 122, Issue 6
Table of Contents

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Special Report

Potency and kinetics of nitric oxide-mediated vascular smooth muscle relaxation determined with flash photolysis of ruthenium nitrosyl chlorides 971
T.D. Carter, N. Bettache & D. Ogden
Abstract    Full Article (PDF)

Papers

Dilatation by angiotensin II of the rat femoral arterial bed in vivo via pressure/flow-induced release of nitric oxide and prostaglandins 975
Akos Heinemann, Christof H. Wachter, Bernhard A. Peskar & Peter Holzer
Abstract    Full Article (PDF)

Contrasting effects of carbachol, McN-A-343 and AHR-602 on Ca2+-mobilization and Ca2+-influx pathways in taenia caeci 985
Shigeru Hishinuma, Ikuko Hongo, Yukio Matsumoto, Fumihiro Narita & Masanori Kurokawa
Abstract    Full Article (PDF)

Subtypes of endothelin receptors that mediate venous effects of endothelin-1 in anaesthetized rats 993
Beatriz Palacios, Su Lin Lim & Catherine C. Y. Pang
Abstract    Full Article (PDF)

Morphological heterogeneity with normal expression but altered function of G proteins in porcine cultured regenerated coronary endothelial cells 999
Catherine Borg-Capra, Marie-Pierre Fournet-Bourguignon, Philip Janiak, Nicole Villeneuve, Jean-Pierre Bidouard, Jean-Paul Vilaine & Paul M. Vanhoutte
Abstract    Full Article (PDF)

Quantification and distribution of alpha1-adrenoceptor subtype mRNAs in human vas deferens: comparison with those of epididymal and pelvic portions 1009
Nobuo Moriyama, Kimio Nasu, Takumi Takeuchi, Katsuyoshi Akiyama, Satoshi Murata, Hiroaki Nishimatsu, Junichi Yano, Gozoh Tsujimoto & Kazuki Kawabe
Abstract    Full Article (PDF)

Effect of thromboxane A2 antagonists on bronchial hyperresponsiveness induced immediately after interleukin-8 inhalation in guinea-pigs 1015
Masaki Fujimura, Shigeharu Myou, Masaharu Nomura, Tamotsu Matsuda, Akihisa Harada, Naofumi Mukaida, Kouji Matsushima & Akitaka Nonomura
Abstract    Full Article (PDF)

Fidelity in functional coupling of the rat P2Y1 receptor to phospholipase C 1021
Joel B. Schachter, José L. Boyer, Qing Li, Robert A. Nicholas & T. Kendall Harden
Abstract    Full Article (PDF)

Hexamethonium- and methyllycaconitine-induced changes in acetylcholine release from rat motor nerve terminals 1025
>Lijun Tian, Chris Prior, John Dempster & Ian G. Marshall
Abstract    Full Article (PDF)

Ethanol inhibition of N-methyl-D-aspartate-activated current in mouse hippocampal neurones: whole-cell patch-clamp analysis 1035
Robert W. Peoples, Geoffrey White, David M. Lovinger & Forrest F. Weight
Abstract    Full Article (PDF)

Nitrergic modulation of cholinergic responses in the opossum lower oesophageal sphincter 1043
Selim Cellek & Salvador Moncada
Abstract    Full Article (PDF)

Effect of pentoxifylline on the degradation of procollagen type I produced by human hepatic stellate cells in response to transforming growth factor-beta1 1047
Roberto Giulio Romanelli, Alessandra Caligiuri, Vinicio Carloni, Raffaella DeFranco, Paolo Montalto, Elisabetta Ceni, Alessandro Casini, Paolo Gentilini & Massimo Pinzani
Abstract    Full Article (PDF)

Effects of dexamethasone and phorbol ester on P2 receptor-coupled Ca2+ signalling and lipocortin 1 presentation in U937 cells 1055
Nicholas J. Willmott, Qam Choudhury & Roderick J. Flowers
Abstract    Full Article (PDF)

Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells in vitro and angiogenesis in vivo 1061
Masayuki Isaji, Hiroshi Miyata, Yoshiyuki Ajisawa, Yasuo Takehana & Nagahisa Yoshimura
Abstract    Full Article (PDF)

beta-Adrenoceptor-mediated inhibition of alpha1-adrenoceptor-mediated and field stimulation-induced contractile responses in the prostate of the guinea pig 1067
John M. Haynes & Stephen J. Hill
Abstract    Full Article (PDF)

Calcium mobilization in Jurkat cells via A2b adenosine receptors 1075
Maribel Mirabet, Josefa Mallol, Carmen Lluis & Rafael Franco
Abstract    Full Article (PDF)

Effect of peroxynitrite on plasma extravasation, microvascular blood flow and nociception in the rat 1083
V.C. Ridger, S.A.B. Greenacre, R.L.C. Handy, B. Halliwell, P.K. Moore, M. Whiteman & S.D. Brain
Abstract    Full Article (PDF)

Interaction of the renin – angiotensin system, bradykinin and sympathetic nerves with cholinergic transmission in the rat isolated trachea 1089
Maurice E. Fabiani, Diem T. Dinh & David F. Story
Abstract    Full Article (PDF)

GR144053, a fibrinogen receptor antagonist, enhances the suppression of neointima formation by losartan, an angiotensin II receptor antagonist, in the injured carotid artery of hamster 1099
Hiroyuki Matsuno, Osamu Kozawa, Masayuki Niwa, Takehiro Kaida, Hideharu Hayashi & Toshihiko Uematsu
Abstract    Full Article (PDF)

The influence of 5-HT2 and 5-HT4 receptor antagonists to modify drug induced disinhibitory effects in the mouse light/dark test 1105
Brenda Costall & Robert J. Naylor
Abstract    Full Article (PDF)

Binding and effects of KATP channel openers in the vascular smooth muscle cell line, A10 1119
Ulrich Russ, Friedrich Metzger, Elisabeth Kickenweiz, Annette Hambrock, Peter Krippeit-Drews & Ulrich Quast
Abstract    Full Article (PDF)

Tumour necrosis factor-alpha expression and cell recruitment in Sephadex particle-induced lung inflammation: effects of dexamethasone and cyclosporin A 1127
Cara M.M. Williams, Lance Smith, Brian F. Flanagan, L. Steve Clegg & John W. Coleman
Abstract    Full Article (PDF)

Investigation of the role of nitric oxide and cyclic GMP in both the activation and inhibition of human neutrophils 1135
P. Wanikiat, D.F. Woodward & R.A. Armstrong
Abstract    Full Article (PDF)

Inhibition by levetiracetam of a non-GABAA receptor-associated epileptiform effect of bicuculline in rat hippocampus 1146
Doru Georg Margineanu & Ernst Wülfert
Abstract    Full Article (PDF)

Electrophysiological characterisation of tachykinin receptors in the rat nucleus of the solitary tract and dorsal motor nucleus of the vagus in vitro 1151
Karen A. Maubach & Roland S.G. Jones
Abstract    Full Article (PDF)

Cardiac inotropes inhibit the oedema caused by nifedipine in rabbit skin 1160
Morteza Taherzadeh & John B. Warren
Abstract    Full Article (PDF)

Activation of the cAMP transduction cascade contributes to the mechanical hyperalgesia and allodynia induced by intradermal injection of capsaicin 1165
Kathleen A. Sluka
Abstract    Full Article (PDF)

Evidence for a 5-HT3 receptor involvement in the facilitation of peristalsis on mucosal application of 5-HT in the guinea pig isolated ileum 1174
B.R. Tuladhar, M. Kaisar & R.J. Naylor
Abstract    Full Article (PDF)

Intravascular and interstitial degradation of bradykinin in isolated perfused rat heart 1179
Andreas Dendorfer, Sebastian Wolfrum, Peter Wellhöner, Katja Korsman & Peter Dominiak
Abstract    Full Article (PDF)

FcRI-mediated chloride uptake by rat mast cells: modulation by chloride transport inhibitors in relation to histamine secretion 1188
A.C. Redrup, J.C. Foreman, N.A. Hayes & F.L. Pearce
Abstract    Full Article (PDF)

Modulation of nicotinic ACh-, GABAA– and 5-HT3-receptor functions by external H-7, a protein kinase inhibitor, in rat sensory neurones 1195
Hong-Zhen Hu & Zhi-Wang Li
Abstract    Full Article (PDF)

Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists 1202
Takuya Maemoto, Keith Finlayson, Henry J. Olverman, Atsushi Akahane, Roger W. Horton & Steven P. Butcher
Abstract    Full Article (PDF)

Effect of lacidipine on cholesterol esterification: in vivo and in vitro studies 1209
F. Bernini, M. Canavesi, E. Bernardini, N. Scurati, S. Bellosta & R. Fumagalli
Abstract    Full Article (PDF)

Reversal of tolerance to the antitransit effects of morphine during acute intestinal inflammation in mice 1216
Olga Pol & Margarita M. Puig
Abstract    Full Article (PDF)

Effects of a novel guanylate cyclase inhibitor on nitric oxide-dependent inhibitory neurotransmission in canine proximal colon 1223
H. Franck, K.M. Sweeney, K.M. Sanders & C.W.R. Shuttleworth
Abstract    Full Article (PDF)

Structural requirements for roxatidine in the stimulant effect of rat gastric mucin synthesis and the participation of nitric oxide in this mechanism 1230
Takafumi Ichikawa, Kazuhiko Ishihara, Katsunori Saigenji & Kyoko Hotta
Abstract    Full Article (PDF)

Acute effects of nitric oxide blockade with L-NAME on arterial haemodynamics in the rat 1237
Cheng-Tao Hu, Kuo-Chu Chang, Chia-Yen Wu & Hsing I. Chen
Abstract    Full Article (PDF)

Lipolytic effects of conventional beta3-adrenoceptor agonists and of CGP 12,177 in rat and human fat cells : preliminary pharmacological evidence for a putative beta4-adrenoceptor 1244
Jean Galitzky, Dominique Langin, Patrick Verwaerde, Jean-Louis Montastruc, Max Lafontan & Michel Berlan
Abstract    Full Article (PDF)

Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion 1251
T. Takasago, E.E. Peters, D.I. Graham, H. Masayasu & I.M. Macrae
Abstract    Full Article (PDF)


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