T Kajiume1,2, A Nagita1, S Yoshimi2, K Kobayashi1 & N Kataoka1
1Department of Pediatrics, Kawasaki Medical School, Okayama, Japan
2Satou Memorial Hospital, Okayama, Japan
Correspondence to: Dr T Kajiume, Department of Pediatrics, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan
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Hemolytic uremic syndrome (HUS) after transplantation is difficult to treat, and there is no consensus regarding optimal mode of treatment. We attached transdermal isosorbide tape as a nitric oxide (NO) donor to patients with HUS after bone marrow transplantation (BMT). This was very effective in ameliorating the hemolysis and increasing platelet numbers. We report here the successful use of an isosorbide in a patient with HUS after transplantation. Bone Marrow Transplantation (2000) 25, 109–110.
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