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British Journal of Pharmacology

January 1999, Volume 126, Issue 1
Table of Contents

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Original Articles

Inhibition of endothelium-dependent hyperpolarization by endothelial prostanoids in guinea-pig coronary artery 1
Kazuhiro Yajima, Makoto Nishiyama, Yoshimichi Yamamoto & Hikaru Suzuki
Abstract    Full Article (PDF)

Effects of Ca2+ concentration and Ca2+ channel blockers on noradrenaline release and purinergic neuroeffector transmission in rat tail artery 11
James A. Brock & Thomas C. Cunnane
Abstract    Full Article (PDF)

Acetylcholine-induced membrane potential changes in endothelial cells of rabbit aortic valve 19
Masuo Ohashi, Kohichi Satoh & Takeo Itoh
Abstract    Full Article (PDF)

Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist 27
Gudrun V. Skuladottir, Logi Jonsson, Jon O. Skarphedinsson, Felikss Mutulis, Ruta Muceniece, Amanda Raine, Ilze Mutule, Johannes Helgason, Peteris Prusis, Jarl E.S. Wikberg & Helgi B. Schiöth
Abstract    Full Article (PDF)

The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation 35
Céline Rouaud, Marcel Delaforge, Marielle Anger-Leroy, Gaël Le Filliatre, Michel Finet & Rémy Hanf
Abstract    Full Article (PDF)

Cytokine-mediated inflammatory hyperalgesia limited by interleukin-4 45
F.Q. Cunha, S. Poole, B.B. Lorenzetti, F.H. Veiga & S.H. Ferreira
Abstract    Full Article (PDF)

Dual actions of the metabolic inhibitor, sodium azide on KATP channel currents in the rat CRI-G1 insulinoma cell line 51
J. Harvey, S.C. Hardy & M.L.J. Ashford
Abstract    Full Article (PDF)

Enantioselective inhibition of the biotransformation and pharmacological actions of isoidide dinitrate by diphenyleneiodonium sulphate 61
Jodan D. Ratz, John J. McGuire & Brian M. Bennett
Abstract    Full Article (PDF)

Homologous regulation of the alpha2C-adrenoceptor subtype in human hepatocarcinoma, HepG2 69
Cécile Cayla, Stéphane Schaak, Cyril Roquelaine, Céline Gales, Françoise Quinchon & Hervé Paris
Abstract    Full Article (PDF)

Proliferative effects of cholecystokinin in GH3 pituitary cells mediated by CCK2 receptors and potentiated by insulin 79
Alison J. Smith & Ruth M. McKernan
Abstract    Full Article (PDF)

Taurine modulates IKr but not IKs in guinea-pig ventricular cardiomyocytes 87
Hiroyasu Satoh
Abstract    Full Article (PDF)

Nitric oxide limits the eicosanoid-dependent bronchoconstriction and hypotension induced by endothelin-1 in the guinea-pig 93
Karina Lewis, Alain Cadieux, Giles A. Rae, Jean-Philippe Gratton & Pedro D'Orléans-Juste
Abstract    Full Article (PDF)

Transcriptional down-regulation of the rabbit pulmonary artery endothelin B receptor during phenotypic modulation 103
R. Owe-Young, C.G. Schyvens, R.A. Qasabian, A.D. Conigrave, P.S. Macdonald & D.J. Williamson
Abstract    Full Article (PDF)

Role of iNOS in the vasodilator responses induced by L-arginine in the middle cerebral artery from normotensive and hypertensive rats 111
Ana M. Briones, María J. Alonso, Jesús Marín & Mercedes Salaices
Abstract    Full Article (PDF)

NMDA receptor characterization and subunit expression in rat cultured mesencephalic neurones 121
C. Allgaier, P. Scheibler, D. Müller, T.J. Feuerstein & P. Illes
Abstract    Full Article (PDF)

Two affinities for a single antagonist at the neuronal NK1 tachykinin receptor: evidence from quantitation of receptor endocytosis 131
Karl M. Jenkinson, Bridget R. Southwell & John B. Furness
Abstract    Full Article (PDF)

A comparison of an A1 adenosine receptor agonist (CVT-510) with diltiazem for slowing of AV nodal conduction in guinea-pig 137
Stephen Snowdy, Hui Xiu Liang, Brent Blackburn, Robert Lum, Marek Nelson, Lisa Wang, Jürg Pfister, Bhavender P. Sharma, Andrew Wolff & Luiz Belardinelli
Abstract    Full Article (PDF)

Neuroregulation by vasoactive intestinal peptide (VIP) of mucus secretion in ferret trachea: activation of BKCa channels and inhibition of neurotransmitter release 147
Yu-Chih Liu, Hema J. Patel, Aamir M. Khawaja, Maria G. Belvisi & Duncan F. Rogers
Abstract    Full Article (PDF)

Effect of acute and long-term treatment with 17-beta-estradiol on the vasomotor responses in the rat aorta 159
Heidi L. Andersen, Jan U. Weis, Bjarne Fjalland & Niels Korsgaard
Abstract    Full Article (PDF)

Differences in the actions of some blockers of the calcium-activated potassium permeability in mammalian red cells 169
D.C.H. Benton, C.J. Roxburgh, C.R. Ganellin, M.A.R. Shiner & D.H. Jenkinson
Abstract    Full Article (PDF)

[3H]-Mesulergine labels 5-HT7 sites in rat brain and guinea-pig ileum but not rat jejunum 179
Maggie Hemedah, Ian M. Coupar & Fred J. Mitchelson
Abstract    Full Article (PDF)

Effects of tumour necrosis factor-alpha on left ventricular function in the rat isolated perfused heart: possible mechanisms for a decline in cardiac function 189
N.J. Edmunds, H. Lal & B. Woodward
Abstract    Full Article (PDF)

Reduction of sodium deoxycholic acid-induced scratching behaviour by bradykinin B2 receptor antagonists 197
Izumi Hayashi & Masataka Majima
Abstract    Full Article (PDF)

Antagonist activity of alpha-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells 205
A.J. Doherty, G.L. Collingridge & D.E. Jane
Abstract    Full Article (PDF)

Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia 211
Hiroshi Masuda, Moritaka Goto, Satoru Tamaoki & Hiroshi Azuma
Abstract    Full Article (PDF)

Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice 219
Thierry Chataigneau, Michel Félétou, Paul L. Huang, Mark C. Fishman, Jacques Duhault & Paul M. Vanhoutte
Abstract    Full Article (PDF)

Effects of heptanol on the neurogenic and myogenic contractions of the guinea-pig vas deferens 227
K. Venkateswarlu, Sumedha Y. Dange & Rohit Manchanda
Abstract    Full Article (PDF)

Improvement by nefiracetam of beta-amyloid-(1-42)-induced learning and memory impairments in rats 235
Kiyofumi Yamada, Tomoko Tanaka, Takayoshi Mamiya, Tadashi Shiotani, Tsutomu Kameyama & Toshitaka Nabeshima
Abstract    Full Article (PDF)

Mibefradil (Ro 40-5967) inhibits several Ca2+ and K+ currents in human fusion-competent myoblasts 245
Jian-Hui Liu, Philippe Bijlenga, Teresa Occhiodoro, Jacqueline Fischer-Lougheed, Charles R. Bader & Laurent Bernheim
Abstract    Full Article (PDF)

Effects of phrixotoxins on the Kv4 family of potassium channels and implications for the role of Ito1 in cardiac electrogenesis 251
Sylvie Diochot, Milou-Daniel Drici, Danielle Moinier, Michel Fink & Michel Lazdunski
Abstract    Full Article (PDF)

In vivo demonstration of H3-histaminergic inhibition of cardiac sympathetic stimulation by R-alpha-methyl-histamine and its prodrug BP 2.94 in the dog 264
Catherine Mazenot, Christophe Ribuot, Andrée Durand, Yves Joulin, Pierre Demenge & Diane Godin-Ribuot
Abstract    Full Article (PDF)

Modulation of chloride, potassium and bicarbonate transport by muscarinic receptors in a human adenocarcinoma cell line 269
Nicholas D. Holliday & Helen M. Cox
Abstract    Full Article (PDF)

Interaction of amylin with calcitonin gene-related peptide receptors in the microvasculature of the hamster cheek pouch in vivo 280
Judith M. Hall & Susan D. Brain
Abstract    Full Article (PDF)

Selective effects of a 4-oxystilbene derivative on wild and mutant neuronal chick alpha7 nicotinic receptor 285
L. Maggi, E. Palma, F. Eusebi, M. Moretti, B. Balestra, F. Clementi & C. Gotti
Abstract    Full Article (PDF)

Lack of interaction between nitric oxide and the redox modulatory site of the NMDA receptor 296
Elias Aizenman & William K. Potthoff
Abstract    Full Article (PDF)

Modulation of acute and chronic inflammatory processes by cacospongionolide B, a novel inhibitor of human synovial phospholipase A2 301
Pablo García Pastor, Salvatore De Rosa, Alfonso De Giulio, Miguel Payá & M. José Alcaraz
Abstract    Full Article (PDF)

Anaphylactic bronchoconstriction in BP2 mice: interactions between serotonin and acetylcholine 312
Seok-Yong Eum, Xavier Norel, Jean Lefort, Carlos Labat, B. Boris Vargaftig & Charles Brink
Abstract    Full Article (PDF)

Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine 317
Diana M. Barker & Roger Corder
Abstract    Full Article (PDF)

The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat 326
Sara G. Hamilton, Alex Wade & Stephen B. McMahon
Abstract    Full Article (PDF)

Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord 333
Alice M. Holohean, John C. Hackman & Robert A. Davidoff
Abstract    Full Article (PDF)

Effects of pyrogallol, hydroquinone and duroquinone on responses to nitrergic nerve stimulation and NO in the rat anococcygeus muscle 342
Mylinh La & Michael J. Rand
Abstract    Full Article (PDF)

Growth-inhibitory effect of cyclic GMP- and cyclic AMP-dependent vasodilators on rat vascular smooth muscle cells: effect on cell cycle and cyclin expression 349
Nicola Kronemann, Wolfgang A. Nockher, Rudi Busse & Valérie B. Schini-Kerth
Abstract    Full Article (PDF)

Formal analysis of electrogenic sodium, potassium, chloride and bicarbonate transport in mouse colon epithelium 358
A.W. Cuthbert, M.E. Hickman & L.J. MacVinish
Abstract    Full Article (PDF)

Identification of a region of the C-terminal domain involved in short-term desensitization of the prostaglandin EP4 receptor 365
Murat Bastepe & Barrie Ashby
Abstract    Full Article (PDF)

Acute troglitazone action in isolated perfused rat liver 372
Kurt Preininger, Harald Stingl, Rainer Englisch, Clemens Fürnsinn, Jürg Graf, Werner Waldhäusl & Michael Roden
Abstract    Full Article (PDF)

Instructions to Authors

379
Full Article (PDF)

Nomenclature Guidelines for Authors

387
Full Article (PDF)

© Macmillan Publishers Ltd 1999

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