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Human and Experimental Toxicology
Instructions for authors
Human and Experimental Toxicology is the international journal which covers all types of chemical harm to living systems. Papers are published on all aspects of experimental and clinical studies of functional, biochemical, immunological and pathological toxic processes and disorders in vivo and in vitro, on their causal mechanisms, and on toxicity in human and animal patients and on its treatment.
Original research papers, short communications and letters are welcomed. Editorials and reviews are invited but they should first be discussed with an editor. Announcements of meetings are published.
All papers reporting results of investigations in patients and volunteer subjects must indicate that acceptable measures have been taken to obtain informed consent. Investigations in patients and healthy volunteers must indicate that informed consent was properly obtained and that the work was approved by the relevant Research Ethics Committee (IRB).
Reports of experiments involving animals must indicate that national legislation or the equivalent local standard for protecting animal welfare has been followed.
The Editor may alter manuscripts to make them conform to the stylistic and bibliographic conventions of the journal.
Submission of manuscripts
Authors should send two copies of their manuscript and illustrations plus a third photocopy of the illustrations, to: UK, Europe and Far East:
Professor Robert Kroes
Editor-in-Chief
Human & Experimental Toxicology
Seminariehof 38
NL - 3768 EE SOEST
The Netherlands
Tel: +31 (0)35 642 2393
Fax: +31 (0)35 622 3442
E-mail: rmkroes@worldonline.nl
Americas:
Dr A. Wallace Hayes, Vice President
Corporate Product Integrity
The Gillette Company
Prudential Tower Building
Boston, Massachusetts 02199
USA
Tel: +1 617 421 7380
Fax: +1 617 421 7360
To facilitate the processing of papers, authors are required to submit a disk with their final manuscript. The disk should be formatted and prepared using IBM, IBM-compatible or Apple computers, and should be clearly labelled with the file name and the software name and release number.
One author should be clearly designated as correspondent, to whom proofs will also be sent, and the full postal address, telephone number and fax number of this person should be given. Neglecting to include this information may result in delay of publication.
The manuscript should be accompanied by a signed statement to the effect that it is not currently under consideration for publication elsewhere and that the content has not been anticipated by previous publications.
Copyright
Illustrations, tables, or quotations taken from other publications are copyright and can only be reproduced with written permission from the copyright owner. Send author's and publisher's written permission with the manuscript.
Presentation
Manuscripts should be typed, double-spaced, on one side of the paper only, and should be structured into sections as follows:
Title page;
Summary and keywords;
Introduction;
Methods;
Results;
Discussion;
Acknowledgements (details of supporting grants, permission for reproduction of copyright materials, etc.);
References.
Each section should begin on a new sheet. Other subsection headings within these main sections may be used but should be limited. The main title should be explicit and specific (80 character limit) and an abbreviated (running) title (40-50 character limit) should be given. The summary should form a synopsis of the work, at the same time underlining the contribution of the research to the understanding of toxicology; it should be less than 200 words in length. Keywords (3-6) must be supplied otherwise the paper cannot be included in the annual index.
Style
For style information and lists of standard abbreviations, consult the American Medical Association Manual of Style: A Guide for Authors and Editors, 9th Edition (Baltimore: Williams & Wilkins,1998). Use metric units throughout the manuscript. The use of footnotes is not permitted. Single quotation marks should be used throughout. Words to be italicised should be underlined. Whenever possible drugs should be referred to by their generic name rather than by a proprietary name. When a proprietary name must be used, it should begin with a capital letter to indicate this.
References
References should be numbered consecutively in the order that they are first mentioned in the text, and these numbers should be inserted above the line each time the author is cited, eg '...As others have done.2-5,7 The full list of references at the end of the article should be arranged in numerical order. Each reference should include the names and initials of all authors, but if there are more than four the first author may be followed by et al, the title of the article, the unabbreviated title of the journal, the year, the volume, and first and last page numbers. Titles of books should be followed by the place of publication, the publisher, and the year. References to 'unpublished observations' or 'personal communications' should be mentioned in the text but not included in the list of references. The titles of periodicals should be unabbreviated. The style is as follows:
- Alcock G, Brown DW. The Minnesota coding of EEGs applied to the evaluation of beta-blockers in ischaemic heart disease. British Medical Journal 1983; 287: 3010-3015.
- Alcock G, Brown DW. The Minnesota Coding of EEGs. Macmillan Press: London, 1983
Illustrations
All illustrations (photographs or line drawings) should be about 1.5 times the intended final size. The proportions of the printed page should be borne in mind when authors are preparing the format of illustrations. Glossy prints of photographs are necessary. Any lettering or annotation on photographs or line drawings should be indicated on a tracing overlay or a photocopy of the original. The use of symbols should be consistent. All illustrations should be identified on the back by the name of the principal author and the figure number. If the orientation of an illustration is not obvious it should be indicated on the back. All illustrations should be numbered as figures whether they are photographs, representational drawings or graphs, i.e. Figure 1, Figure 2, Figure 3. Captions for illustrations should be collected together and presented on a separate page. All illustrations should be specifically referred to in the text. Authors will be expected to defray the extra cost of printing any illustrations in colour, estimated at $1000 for the first page and $500 for each additional page. Electronic submission of figures is encouraged. The preferred formats include .EPS and .TIF. Preferred programs include Photoshop, Illustrator and CorelDraw.
Tables
Tables ideally should not have more than 80, and certainly not more than 100, characters to the line (counting spaces between columns as 4 characters) unless absolutely unavoidable. Each table should be on a separate page with its caption. All tables should be specifically referred to in the text.
Proofs
The designated author will receive one copy of the proof which should be corrected and returned promptly to the Publisher using the address label provided. Authors will be asked to defray the expense of any alteration after proofing which represents a major departure from the original copy.
Offprints
Twenty-five offprints of each article will be provided free of charge. Additional offprints can be ordered on the form accompanying the proofs.
Business correspondence and enquiries relating to advertising, subscriptions, backnumbers or reprints should be addressed to Jennifer English at Specialist Journals Division, Nature Publishing Group, 345 Park Avenue South, New York, NY 10010-1707, USA.
Last Updated 23 February 2001
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