Gene Therapy

June 1998, Volume 5, Issue 6
Table of Contents

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News and Comments

GT News 723
Full Article (PDF)

Editorial

Adenoviral vectors: not to be sneezed at 725
PF Searle & V Mautner
Full Article (PDF)

Review

Cell death and cancer: replacement of apoptotic genes and inactivation of death suppressor genes in therapy 728
M Favrot, J-L Coll, N Louis & A Negoescu
Abstract    Full Article (PDF)

Papers

Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo 740
SJ Beer, CB Matthews, CS Stein, BD Ross, JM Hilfinger & BL Davidson
Abstract    Full Article (PDF)

Adenovirus-mediated wild-type p53 overexpression inhibits endothelial cell differentiation in vitro and angiogenesis in vivo 747
T Riccioni, C Cirielli, X Wang, A Passaniti & MC Capogrossi
Abstract    Full Article (PDF)

A novel method for the direct quantification of gene transfer into cells using PCR in situ 755
C Catzavelos, C Ruedy, AK Stewart & I Dubé
Abstract    Full Article (PDF)

Inhibition of intimal hyperplasia after vein grafting by in vivo transfer of human senescent cell-derived inhibitor-1 gene 761
H Bai, R Morishita, I Kida, T Yamakawa, W Zhang, M Aoki, H Matsushita, A Noda, R Nagai, Y Kaneda, J Higaki, T Ogihara, Y Sawa & H Matsuda
Abstract    Full Article (PDF)

Recombinant adenoviral delivery for in vivo expression of scFv antibody fusion proteins 770
HA Whittington, LJ Ashworth & RE Hawkins
Abstract    Full Article (PDF)

IL-1/IL-3 gene therapy of non-small cell lung cancer (NSCLC) in rats using ‘cracked’ adenoproducer cells 778
MC Esandi, GD van Someren, A Bout, AH Mulder, DW van Bekkum, D Valerio & JL Noteboom
Abstract    Full Article (PDF)

Superiority of the ear pinna over muscle tissue as site for DNA vaccination 789
P Förg, P von Hoegen, W Dalemans & V Schirrmacher
Abstract    Full Article (PDF)

Imaging and tissue biodistribution of 99mTc-labeled adenovirus knob (serotype 5) 798
KR Zinn, JT Douglas, CA Smyth, H-G Liu, Q Wu, VN Krasnykh, JD Mountz, DT Curiel & JM Mountz
Abstract    Full Article (PDF)

Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector 809
U Herrlinger, CM Kramm, KS Aboody-Guterman, JS Silver, K Ikeda, KM Johnston, PA Pechan, RF Barth, D Finkelstein, EA Chiocca, DN Louis & XO Breakefield
Abstract    Full Article (PDF)

In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector 820
MJ During, RJ Samulski, JD Elsworth, MG Kaplitt, P Leone, X Xiao, J Li, A Freese, JR Taylor, RH Roth, JR Sladek Jr, KL O’Malley & DE Redmond Jr
Abstract    Full Article (PDF)

Systemic long-term delivery of antibodies in immunocompetent animals using cellulose sulphate capsules containing antibody-producing cells 828
M Pelegrin, M Marin, D Noël, M Del Rio, R Saller, J Stange, S Mitzner, WH Günzburg & M Piechaczyk
Abstract    Full Article (PDF)

Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro 835
I Hickson, LJ Fairbairn, N Chinnasamy, LS Lashford, N Thatcher, GP Margison, TM Dexter & JA Rafferty
Abstract    Full Article (PDF)

Chemoprotective gene transfer II: multilineage in vivo protection of haemopoiesis against the effects of an antitumour agent by expression of a mutant human O6-alkylguanine-DNA alkyltransferase 842
N Chinnasamy, JA Rafferty, I Hickson, LS Lashford, SJ Longhurst, N Thatcher, GP Margison, TM Dexter & LJ Fairbairn
Abstract    Full Article (PDF)

Targeting of a cholecystokinin-DNA complex to pancreatic cells in vitro and in vivo 848
DS Carpenter & RF Minchin
Abstract    Full Article (PDF)

Brief Communication

Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles 855
A Kichler, W Zauner, M Ogris & E Wagner
Abstract    Full Article (PDF)


© Macmillan Publishers Ltd 1998

As part of one of the world's largest publishers, Stockton Press has a substantial list of leading international journals in the key areas of science and medicine. Specialist fields covered include: bone marrow transplantation, cell death and differentiation, critical care/intensive care, dentistry, dentomaxillofacial radiology, gene therapy, haematology, human and experimental toxicology, human hypertension, impotence research, industrial microbiology, information systems, leukemia, lupus, molecular psychiatry, multiple sclerosis, neuroscience, nursing, nutrition, obesity, oncology, operations research, optometry and ophthalmology, oral diseases, orthopaedics, paraplegia, pharmacology, psychiatry, public health, spinal injury and disease.