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Leukemia
Normal and Malignant Hemopoiesis

November 1999, Volume 13, Issue 11
Table of Contents

Journal Home
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Leading Article

Forced expression of the leukemia-associated gene EVI1 in ES cells: a model for myeloid leukemia with 3q26 rearrangements 1639
S Sitailo, R Sood, K Barton & G Nucifora
Abstract    Full Article (PDF)

Reviews

Chronic myeloid leukemia from basics to bedside 1646
SFT Thijsen, GJ Schuurhuis, JW van Oostveen & GJ Ossenkoppele
Abstract    Full Article (PDF)

The role of Homeobox genes in normal hematopoiesis and hematological malignancies 1675
JW van Oostveen, JJ Bijl, FM Raaphorst, JJM Walboomers & CJLM Meijer
Abstract    Full Article (PDF)

Clinical relevance of minimal residual disease monitoring in non-Hodgkin’s lymphomas: a critical reappraisal of molecular strategies 1691
P Corradini, M Ladetto, A Pileri & C Tarella
Abstract    Full Article (PDF)

Original Manuscripts

Childhood ALL, Prognosis
Significance of commonly used prognostic factors differs for children with T cell acute lymphocytic leukemia (ALL), as compared to those with B-precursor ALL. A Pediatric Oncology Group (POG) study 1696
J Pullen, JJ Shuster, M Link, M Borowitz, M Amylon, AJ Carroll, V Land, AT Look, B McIntyre & B Camitta
Abstract    Full Article (PDF)

TEL-AML1 fusion identifies a subset of children with standard risk acute lymphoblastic leukemia who have an excellent prognosis when treated with therapy that includes a single delayed intensification 1708
KW Maloney, L McGavran, JR Murphy, LF Odom, L Stork, Q Wei & SP Hunger
Abstract    Full Article (PDF)

Detection of MLL gene rearrangement
Comparison of cytogenetics, Southern blotting, and fluorescence in situ hybridization as methods for detecting MLL gene rearrangements in children with acute leukemia and with 11q23 abnormalities 1713
S Mathew, FG Behm, J Dalton & SC Raimondi
Abstract    Full Article (PDF)

Atypical B Cell Leukemias: Diagnosis
FISH analysis for BCL-1 rearrangements and trisomy 12 helps the diagnosis of atypical B cell leukaemias 1721
E Matutes, P Carrara, L Coignet, V Brito-Babapulle, N Villamor, A Wotherspoon & D Catovsky
Abstract    Full Article (PDF)

MDS: Prognosis
New system for assessing the prognosis of refractory anemia patients 1727
A Matsuda, I Jinnai, F Yagasaki, S Kusumoto, I Murohashi, M Bessho, K Hirashima, S Honda, M Minamihisamatsu, K Fuchigami, T Matsuo, K Kuriyama & M Tomonaga
Abstract    Full Article (PDF)

Secondary AML
Secondary acute myeloid leukemia with inv(16): report of two cases following paclitaxel-containing chemotherapy and review of the role of intensified ara-C therapy 1735
JF Seymour, SK Juneja, LJ Campbell, PH Ellims, EH Estey & HM Prince
Abstract    Full Article (PDF)

Myelofibrosis
Initial (prefibrotic) stages of idiopathic (primary) myelofibrosis (IMF) - a clinicopathological study 1741
J Thiele, HM Kvasnicka, B Boeltken, R Zankovich, V Diehl & R Fischer
Abstract    Full Article (PDF)

Clonality Studies in CML
Extensive cytogenetic studies of clonality following interferon-alpha therapy in chronic myeloid leukemia occurring in monosomic cells in a patient with Turner syndrome mosaic 1749
A Takeshita, K Shinjo, M Yamashita, S Fujisawa, K Naito, K Ohnishi, K Takahashi, H Matsui & R Ohno
Abstract    Full Article (PDF)

Molecular Cytogenetics
Molecular analysis of chromosomal breakpoints in three examples of chromosomal translocation involving the TEL gene 1754
SP Romana, H Poirel, V Della Valle, M Mauchauffé, M Busson-Le Coniat, R Berger & OA Bernard
Abstract    Full Article (PDF)

Tumor Suppressor Genes-Clinical Correlates
Expression of p16INK4A and p14ARF in hematological malignancies 1760
T Taniguchi, N Chikatsu, S Takahashi, A Fujita, K Uchimaru, S Asano, T Fujita & T Motokura
Abstract    Full Article (PDF)

"Leukemicness" of Early Progenitors in AML
Detection of cytogenetic aberrations both in CD90 (Thy-1)-positive and (Thy-1)-negative stem cell (CD34) subfractions of patients with acute and chronic myeloid leukemias 1770
C Brendel, B Mohr, C Schimmelpfennig, J Müller, M Bornhäuser, M Schmidt, M Ritter, G Ehninger & A Neubauer
Abstract    Full Article (PDF)

Gene Therapy
Protection of committed murine haemopoietic progenitors against BCNU toxicity does not predict protection of primitive, multipotent spleen colony-forming cells - implications for chemoprotective gene therapy 1776
N Chinnasamy, JA Rafferty, LS Lashford, D Chinnasamy, GP Margison, N Thatcher, TM Dexter & LJ Fairbairn
Abstract    Full Article (PDF)

Open Forum

Selective pressure as an essential force in molecular evolution of myeloid leukemic clones: a view from the window of Fanconi anemia 1784
MW Lensch, RK Rathbun, SB Olson, GR Jones & GC Bagby Jr
Abstract    Full Article (PDF)

Animal Models: Chronic Myeloproliferative Disorders
The Tel-PDGFRbeta fusion gene produces a chronic myeloproliferative syndrome in transgenic mice 1790
KA Ritchie, AAG Aprikyan, DF Bowen-Pope, CJ Norby-Slycord, S Conyers, SH Bartelmez, E Sitnicka & DD Hickstein
Abstract    Full Article (PDF)

Lymphoma
Frequent allelic imbalance but infrequent microsatellite instability in gastric lymphoma 1804
MA Hoeve, SC Ferreira Mota, E Schuuring, WJF de Leeuw, A Chott, JPP Meijerink, PhM Kluin & JHJM van Krieken
Abstract    Full Article (PDF)

Myeloma
Detection of MUM1/IRF4-IgH fusion in multiple myeloma 1812
S Yoshida, N Nakazawa, S Iida, Y Hayami, S Sato, A Wakita, S Shimizu, M Taniwaki & R Ueda
Abstract    Full Article (PDF)

TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells 1817
Y Gazitt
Abstract    Full Article (PDF)

Biotechnical Methods Section (BTS)

Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR 1825
M Emig, S Saußele, H Wittor, A Weißer, A Reiter, A Willer, U Berger, R Hehlmann, NCP Cross & A Hochhaus
Abstract    Full Article (PDF)

Real-time t(11;14) and t(14;18) PCR assays provide sensitive and quantitative assessments of minimal residual disease (MRD) 1833
K Olsson, CJ Gerard, J Zehnder, C Jones, R Ramanathan, C Reading & EG Hanania
Abstract    Full Article (PDF)

Quantitation of leukemia clone-specific antigen gene rearrangements by a single-step PCR and fluorescence-based detection method 1843
SP Mayer, J Giamelli, C Sandoval, AS Roach, M Fevzi Ozkaynak, O Tugal, G Rovera & S Jayabose
Abstract    Full Article (PDF)

Gieseler Papers On Apoptosis Research

Introduction
Apoptosis research is saving the reputation of chemotherapy 1853
F Gieseler & V Nuessler
Full Article (PDF)

Review

Gieseler Papers On Apoptosis Research
Cytotoxic drugs and the CD95 pathway 1854
C Friesen, S Fulda & K-M Debatin
Abstract    Full Article (PDF)

Gieseler Papers On Apoptosis Research

Papers
Molecular effects of topoisomerase II inhibitors in AML cell lines: correlation of apoptosis with topoisomerase II activity but not with DNA damage 1859
F Gieseler, E Bauer, V Nuessler, M Clark & S Valsamas
Abstract    Full Article (PDF)

Bcl-2, bax and bcl-xL expression in human sensitive and resistant leukemia cell lines 1864
V Nuessler, O Stötzer, E Gullis, R Pelka-Fleischer, A Pogrebniak, F Gieseler & W Wilmanns
Abstract    Full Article (PDF)

Drug-induced apoptosis in chronic lymphocytic leukemia 1873
OJ Stoetzer, A Pogrebniak, M Scholz, R Pelka-Fleischer, E Gullis, M Darsow, V Nüssler & W Wilmanns
Abstract    Full Article (PDF)

Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid 1881
M Andreeff, S Jiang, X Zhang, M Konopleva, Z Estrov, VE Snell, Z Xie, MF Okcu, G Sanchez-Williams, J Dong, EH Estey, RC Champlin, SM Kornblau, JC Reed & S Zhao
Abstract    Full Article (PDF)

Correspondence

Two cases of very late relapsing ALL carrying the TEL:AML1 fusion gene 1893
CD Chow, L Dalla-Pozza, DJ Gottlieb & MS Hertzberg
Full Article (PDF)

Mutations of the BCL10 gene are not associated with the blast crisis of chronic myeloid leukaemia 1894
S Bose, JM Goldman & JV Melo
Full Article (PDF)

Treatment of red cell aplasia in CLL with fludarabine 1897
I Ribeiro, C Tsatalas & D Catovsky
Full Article (PDF)

UV and clean air result in contamination-free PCR 1898
RA Padua, A Parrado, J Larghero & C Chomienne
Full Article (PDF)

© Macmillan Publishers Ltd 1999

As part of one of the world's largest publishers, Stockton Press has a substantial list of leading international journals in the key areas of science and medicine. Specialist fields covered include: bone marrow transplantation, cell death and differentiation, critical care/intensive care, dentistry, dentomaxillofacial radiology, environmental epidemiology, gene therapy, hematology, human and experimental toxicology, exposure analysis, human hypertension, impotence research, industrial microbiology, industrial health, information systems, leukemia, lupus, microcirculation, molecular psychiatry, multiple sclerosis, neuroscience, nursing, nutrition, obesity, occupational medicine, oncology, oncology pharmacy practice, operations research, optometry and ophthalmology, oral diseases, orthopedics, paraplegia, perinatology, pharmacology, psychiatry, public health, spinal injury and disease.