Molecular Psychiatry

March 1997, Volume 2, Issue 2
Table of Contents

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General Summary

81
J Licinio & R Lisman
Full Article (PDF)

Guest Editorial

Cytokines in the brain: neuropathological aspects 83
R Dantzer
Full Article (PDF)

News & Views

Schizophrenia, tardive dyskinesia, and a D3 receptor gene variant: a new twist on dyskinesias? 86
DV Jeste & JR Kelsoe
Abstract    Full Article (PDF)

Complex traits, complex answers 89
D Gurwitz
Abstract    Full Article (PDF)

State Of The Art

Inflammatory mechanisms in Alzheimer disease: the role of beta-amyloid/glial interactions 91
JS Pachter
Abstract    Full Article (PDF)

Cytokines In The Brain

Antigen presentation in the CNS 96
K Frei & A Fontana
Full Article (PDF)

Interleukin 1 receptor antagonist gene expression in rat pituitary in the systemic inflammatory response syndrome: pathophysiological implications 99
J Licinio & M-L Wong
Abstract    Full Article (PDF)

Mouse Moloney leukemia virus infects microglia but not neurons even though it induces motor neuron disease 104
JF Zachary, TV Baszler, RA French & KW Kelley
Abstract    Full Article (PDF)

Cytokines secreted by glial cells infected with HTLV-I modulate the expression of matrix metalloproteinases (MMPs) and their natural inhibitor (TIMPs): possible involvement in neurodegenerative processes 107
P Giraudon, S Buart, A Bernard & M-F Belin
Abstract    Full Article (PDF)

Neuropathogenesis of HIV-1 infection: interactions between interleukin-1 and transforming growth factor-beta1 111
L Vitkovic acute
Abstract    Full Article (PDF)

Both soluble and membrane-associated TNF activate brain microvascular endothelium: relevance to multiple sclerosis 113
D Burger, J Lou, J-M Dayer & GE Grau
Full Article (PDF)

The kinetics and regulation of the induction of type II nitric oxide synthase and nitric oxide in human fetal glial cell cultures 117
M Ding & JE Merrill
Abstract    Full Article (PDF)

Cytokines and acute neurodegeneration 120
NJ Rothwell
Full Article (PDF)

Regulation of ICE activity and ICE isoforms by LPS 122
S Tingsborg, M Ziólkowska, M Zetterström, H Hasanvan & T Bartfai
Abstract    Full Article (PDF)

Transgenic models to assess the pathogenic actions of cytokines in the central nervous system 125
IL Campbell, AK Stalder, C-S Chiang, R Bellinger, CJ Heyser, S Steffensen, E Masliah, HC Powell, LH Gold, SJ Henriksen & GR Siggins
Abstract    Full Article (PDF)

Glia-derived cytokines and the biogenesis of amyloid plaques in Alzheimer’s disease 130
AJ Patel, A Jen, C Wickenden, L-S Jen, SM Gentleman & HAR de Silva
Full Article (PDF)

Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue 133
MC Morganti-Kossman, PM Lenzlinger, V Hans, P Stahel, E Csuka, E Ammann, R Stocker, O Trentz & T Kossmann
Abstract    Full Article (PDF)

Therapeutic applications of anti-cytokine strategies 137
S Poole
Full Article (PDF)

Immediate Communications

Dopamine D3-receptor gene variant and susceptibility to tardive dyskinesia in schizophrenic patients 139
VM Steen, R Løvlie, T MacEwan & RG McCreadie
Abstract    Full Article (PDF)

Normal isoform of amyloid protein (PrP) in brains of spawning salmon 146
CJ Gibbs, Jr & CL Bolis
Abstract    Full Article (PDF)

Original Research Articles

Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families 148
RE Straub, CJ MacLean, FA O’Neill, D Walsh & KS Kendler
Abstract    Full Article (PDF)

Evidence suggestive of a locus on chromosome 5q31 contributing to susceptibility for schizophrenia in German and Israeli families by multipoint affected sib-pair linkage analysis 156
SG Schwab, GN Eckstein, J Hallmayer, B Lerer, M Albus, M Borrmann, D Lichtermann, MA Ertl, W Maier & DB Wildenauer
Abstract    Full Article (PDF)

Cannabinoid receptor gene (CNR1): association with IV drug use 161
DE Comings, D Muhleman, R Gade, P Johnson, R Verde, G Saucier & J MacMurray
Abstract    Full Article (PDF)

Association between the cannabinoid receptor gene (CNR1) and the P300 event-related potential 169
JP Johnson, D Muhleman, J MacMurray, R Gade, R Verde, M Ask, J Kelley & DE Comings
Abstract    Full Article (PDF)


© Macmillan Publishers Ltd 1997

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