Multiple Sclerosis

June 1998, Volume 4, Issue 3
Table of Contents

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Original Articles

Neuropathology in multiple sclerosis: new concepts 93
Hans Lassmann
Abstract    Full Article (PDF)

Cerebrospinal fluid - physiology, analysis and interpretation of protein patterns for diagnosis of neurological diseases 99
Hansotto Reiber
Abstract    Full Article (PDF)

Composite cerebrospinal fluid score in relapsing-remitting and secondary progressive multiple sclerosis 108
PJH Jongen, S Floris, WH Doesburg, WAJG Lemmens, OR Hommes & KJB Lamers
Abstract    Full Article (PDF)

The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis 111
H Reiber, S Ungefehr & Chr Jacobi
Abstract    Full Article (PDF)

CSF-enriched antibodies do not share specificities among MS patients 118
I Cortese, S Capone, S Luchetti, LME Grimaldi, A Nicosia & R Cortese
Abstract    Full Article (PDF)

Myelin basic protein in CSF as indicator of disease activity in multiple sclerosis 124
KJB Lamers, HPM de Reus & PJH Jongen
Abstract    Full Article (PDF)

MBP, anti-MBP and anti-PLP antibodies, and intrathecal complement activation in multiple sclerosis 127
Finn Sellebjerg, Michael Christiansen & Peter Garred
Abstract    Full Article (PDF)

Can CSF predict the course of optic neuritis? 132
JL Frederiksen
Abstract    Full Article (PDF)

Immune pathogenesis of multiple sclerosis. Brain autoimmune reactivity and its control by neuronal function 136
Hartmut Wekerle
Abstract    Full Article (PDF)

Are there any body fluid markers of brain atrophy in multiple sclerosis? 138
G Giovannoni, AJE Green & EJ Thompson
Abstract    Full Article (PDF)

Data on cytokine mRNA expression in CSF and peripheral blood mononuclear cells from MS patients as detected by PCR 143
Philippe Monteyne & Christian JM Sindic
Abstract    Full Article (PDF)

Therapy with antibodies against CD40L (CD154) and CD44-variant isoforms reduces experimental autoimmune encephalomyelitis induced by a proteolipid protein peptide 147
JD Laman, CBM Maassen, MM Schellekens, L Visser, M Kap, E de Jong, M van Puijenbroek, MJB van Stipdonk, M van Meurs, C Schwärzler & U Günthert
Abstract    Full Article (PDF)

T cell receptor Vbeta5 and Vbeta17 clonal diversity in cerebrospinal fluid and peripheral blood lymphocytes of multiple sclerosis patients 154
P Lozeron, D Chabas, B Duprey, O Lyon-Caen & R Liblau
Abstract    Full Article (PDF)

Monocyte activation in multiple sclerosis 162
Anthony T Reder, Kurscedilad Genç, Paul V Byskosh & Anna Maria Porrini
Abstract    Full Article (PDF)

Cytokines in multiple sclerosis: pro-inflammation or pro-remyelination? 169
MK Sharief
Abstract    Full Article (PDF)

Time-course analysis of CD25 and HLA-DR expression on lymphocytes in interferon-beta 1b-treated multiple sclerosis patients 174
AM Ferrarini, S Sivieri, M Buttarello, A Facchinetti, P Perini & P Gallo
Abstract    Full Article (PDF)

Correlation of soluble adhesion molecules in blood and cerebrospinal fluid with magnetic resonance imaging activity in patients with multiple sclerosis 178
Peter Rieckmann, Bernd Altenhofen, Antje Riegel, Boris Kallmann & K Felgenhauer
Abstract    Full Article (PDF)

Serum soluble intercellular adhesion molecule-1 in MS: relation to clinical and Gd-MRI activity and to rIFNbeta-1b treatment 183
M Trojano, C Avolio, M Ruggieri, G Defazio, F Giuliani, D Paolicelli & P Livrea
Abstract    Full Article (PDF)

Monitoring Multiple Sclerosis course and activity with TNF-alpha 188
Michel Chofflon & Benoît Fellay
Abstract    Full Article (PDF)

Relapse markers in multiple sclerosis: are in vitro cytokine production changes reflected by circulatory T-cell phenotype alterations? 193
Jan Debruyne, Jan Philippé, Jacques Dereuck, Annick Willems & Geert Leroux-Roels
Abstract    Full Article (PDF)

In vitro cytokine profiles as indicators of relapse activity and clinical course in multiple sclerosis 198
Myriam Schluep, Guy van Melle, Hugues Henry, Claudio Städler, Béatrice Roth-Wicky & Pierre J Magistretti
Abstract    Full Article (PDF)

Myelin reactive T cells in the autoimmune pathogenesis of multiple sclerosis 203
Piet Stinissen, Robert Medaer & Jef Raus
Abstract    Full Article (PDF)

The potential role of nitric oxide in multiple sclerosis 212
G Giovannoni, SJR Heales, JM Land & EJ Thompson
Abstract    Full Article (PDF)

A unique population of circulating autoantibodies promotes central nervous system remyelination 217
K Asakura & M Rodriguez
Abstract    Full Article (PDF)

A gene therapy approach to treat demyelinating diseases using non-replicative herpetic vectors engineered to produce cytokines 222
G Martino, R Furlan, F Galbiati, PL Poliani, A Bergami, LME Grimaldi, L Adorini & G Comi
Abstract    Full Article (PDF)

Are there indicators of remyelination in blood or CSF of multiple sclerosis patients? 228
AR Massaro
Abstract    Full Article (PDF)

Disease activity and the immune set in multiple sclerosis: blood markers for immunotherapy 232
AJ Coles, MG Wing & DAS Compston
Abstract    Full Article (PDF)

The expression of integrins on activated T-cells in multiple sclerosis. Effect of intravenous methylprednisolone treatment 239
S Luján, J Masjuan, E Roldán, LM Villar, P González-Porqué & JC Álvarez-Cermeño
Abstract    Full Article (PDF)

Myelin basic protein-like material in the urine of multiple sclerosis patients: relationships to clinical and neuroimaging changes 243
John N Whitaker
Abstract    Full Article (PDF)

Urinary markers of disease activity in multiple sclerosis 247
G Giovannoni & EJ Thompson
Abstract    Full Article (PDF)

Free light chains in multiple sclerosis urine 254
PD Mehta, SD Cook, PK Coyle, RA Troiano, CS Constantinescu & AM Rostami
Abstract    Full Article (PDF)

Identification of brain atrophy with MRI in MS 257
Alan J Thompson
Abstract    Full Article (PDF)

Neurophysiological and cognitive markers of disease evolution in multiple sclerosis 260
G Comi, V Martinelli, T Locatelli, L Leocani & S Medaglini
Abstract    Full Article (PDF)

Body fluid markers to monitor multiple sclerosis: the assays and the challenges 266
JD Laman, EJ Thompson & L Kappos
Abstract    Full Article (PDF)


© Macmillan Publishers Ltd 1998

As part of one of the world's largest publishers, Stockton Press has a substantial list of leading international journals in the key areas of science and medicine. Specialist fields covered include: bone marrow transplantation, cell death and differentiation, critical care/intensive care, dentistry, dentomaxillofacial radiology, gene therapy, haematology, human and experimental toxicology, human hypertension, impotence research, industrial microbiology, information systems, leukemia, lupus, molecular psychiatry, multiple sclerosis, neuroscience, nursing, nutrition, obesity, oncology, operations research, optometry and ophthalmology, oral diseases, orthopaedics, paraplegia, pharmacology, psychiatry, public health, spinal injury and disease.