Articles
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p53 accumulation in apoptotic macrophages is an energy demanding process that precedes cytochrome c release in response to nitric oxide
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6403
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Florian Brockhaus & Bernhard Brüne
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Abstract Full Article PDF
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Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest
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6411
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Gen Sheng Wu, Timothy F Burns, E Robert McDonald III, Ray D Meng, Gary Kao, Ruth Muschel, Tim Yen & Wafik S El-Deiry
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Abstract Full Article PDF
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A translation repressor element resides in the 3' untranslated region of human p53 mRNA
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6419
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Loning Fu, WeiLi Ma & Samuel Benchimol
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Abstract Full Article PDF
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Functional Rac-1 and Nck signaling networks are required for FGF-2-induced DNA synthesis in MCF-7 cells
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6425
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Jiang-Feng Liu, Eric Chevet, Sem Kebache, Gilles Lemaitre, Denis Barritault, Louise Larose & Michel Crépin
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Abstract Full Article PDF
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Rac regulates the stability of the adherens junction and its components, thus affecting epithelial cell differentiation and transformation
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6434
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Margaret P Quinlan
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Abstract Full Article PDF
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2-Acetaminofluorene blocks cell cycle progression after hepatectomy by p21 induction and lack of Cyclin E expression
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6443
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C Trautwein, M Will, S Kubicka, T Rakemann, P Flemming & M P Manns
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Abstract Full Article PDF
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Inhibitory effect of p21 in MCF-7 cells is overcome by its coordinated stabilization with D-type cyclins
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6454
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Adrian Russell, Joy Hendley & Doris Germain
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Abstract Full Article PDF
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Regulation of BRCA1 by protein degradation
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6460
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Mikhail V Blagosklonny, Won G An, Giovanni Melillo, Phuongmai Nguyen, Jane B Trepel & Leonard M Neckers
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Abstract Full Article PDF
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Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes
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6469
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Mark Nesbit, Heike KE Nesbit, Jean Bennett, Thomas Andl, Mei-Yu Hsu, Emma Dejesus, Michelle McBrian, Abha R Gupta, Stephen L Eck & Meenhard Herlyn
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Abstract Full Article PDF
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LOT1 is a growth suppressor gene down-regulated by the epidermal growth factor receptor ligands and encodes a nuclear zinc-finger protein
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6477
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Abbas Abdollahi, Rudi Bao & Thomas C Hamilton
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Abstract Full Article PDF
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FMIP, a novel Fms-interacting protein, affects granulocyte/macrophage differentiation
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6488
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Teruko Tamura, Annalisa Mancini, Hans Joos, Alexandra Koch, Cosima Hakim, Jan Dumanski, K Michael Weidner & Heiner Niemann
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Abstract Full Article PDF
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VEGI, a new member of the TNF family activates Nuclear Factor- B and c-Jun N-terminal kinase and modulates cell growth
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6496
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Valsala Haridas, Anju Shrivastava, Jeffrey Su, Guo-Liang Yu, Jian Ni, Ding Liu, Su-Fang Chen, Yansong Ni, Steve M Ruben, Reiner Gentz & Bharat B Aggarwal
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Abstract Full Article PDF
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The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but not necrosis of renal epithelial cells
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6505
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Yi Zhan, Bob van de Water, Yuping Wang & James L Stevens
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Abstract Full Article PDF
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Antisense expression for amphiregulin suppresses tumorigenicity of a transformed human breast epithelial cell line
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6513
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Lin Ma, Christiane Gauvillé, Yolande Berthois, Guy Millot, Gibbes R Johnson & Fabien Calvo
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Abstract Full Article PDF
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Testicular wild-type p53 expression in transgenic mice induces spermiogenesis alterations ranging from differentiation defects to apoptosis
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6521
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Isabelle Allemand, Anny Anglo, Anne-Yvonne Jeantet, Italina Cerutti & Evelyne May
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Abstract Full Article PDF
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Activation of Hex and mEg5 by retroviral insertion may contribute to mouse B-cell leukemia
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6531
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G M Hansen & M J Justice
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Abstract Full Article PDF
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A p53 and apoptotic independent role for p21waf1 in tumour response to radiation therapy
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6540
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B G Wouters, N C Denko, A J Giaccia & J M Brown
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Abstract Full Article PDF
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Regulation of the Wilms' tumour suppressor protein transcriptional activation domain
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6546
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Lynn M McKay, Brian Carpenter & Stefan GE Roberts
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Abstract Full Article PDF
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Ras pathway is required for the activation of MMP-2 secretion and for the invasion of src-transformed 3Y1
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6555
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Aye Aye Thant, Thet Thet Sein, Enbo Liu, Kazuya Machida, Fumitaka Kikkawa, Teruhiko Koike, Motoharu Seiki, Satoru Matsuda & Michinari Hamaguchi
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Abstract Full Article PDF
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Protein kinase C- overexpression stimulates Akt activity and suppresses apoptosis induced by interleukin 3 withdrawal
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6564
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Weiqun Li, Jiachang Zhang, Lawrence Flechner, Teresa Hyun, Alan Yam, Thomas F Franke & Jacalyn H Pierce
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Abstract Full Article PDF
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Cytokine response gene 6 induces p21 and regulates both cell growth and arrest
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6573
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Wen Fan, Gunther Richter, Anna Cereseto, Carol Beadling & Kendall A Smith
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Abstract Full Article PDF
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Close correlation between -catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas
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6583
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Benoît Terris, Pascal Pineau, Laurence Bregeaud, Dominique Valla, Jacques Belghiti, Pierre Tiollais, Claude Degott & Anne Dejean
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Abstract Full Article PDF
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Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model
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6589
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Priscilla A Furth, Ud Bar-Peled, Minglin Li, Albert Lewis, Rodolfo Laucirica, Richard Jäger, Hans Weiher & Robert G Russell
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Abstract Full Article PDF
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Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice
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6597
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Kristen L Murphy, Frances S Kittrell, Jason P Gay, Richard Jäger, Daniel Medina & Jeffrey M Rosen
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Abstract Full Article PDF
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BRCA1 signals ARF-dependent stabilization and coactivation of p53
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6605
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Kumaravel Somasundaram, Timothy K MacLachlan, Timothy F Burns, Magda Sgagias, Kenneth H Cowan, Barbara L Weber & Wafik S El-Deiry
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Abstract Full Article PDF
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Short Report
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Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)
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6615
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Sabine Tejpar, Friedel Nollet, Catherine Li, Jay S Wunder, Genevieve Michils, Paola dal Cin, Eric Van Cutsem, Bharati Bapat, Frans van Roy, Jean Jacques Cassiman & Benjamin A Alman
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