Original Articles
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Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis
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1131
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Yongke Zhang, Naoya Fujita & Takashi Tsuruo
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Abstract Full Article PDF
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Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis
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1139
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Alberto Bardelli, Maria Lisa Basile, Enrica Audero, Silvia Giordano, Stefan Wennström, Sylvie Ménard, Paolo M Comoglio & Carola Ponzetto
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Abstract Full Article PDF
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Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation
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1147
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Chris Elly, Stephan Witte, Zhihong Zhang, Olivier Rosnet, Stanley Lipkowitz, Amnon Altman & Yun-Cai Liu
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Abstract Full Article PDF
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11q23.1 and 11q25-qter YACs suppress tumour growth in vivo
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1157
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John Koreth, Christopher J Bakkenist, Zoia Larin, Nicholas CA Hunt, Michael R James & James O'D McGee
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Abstract Full Article PDF
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Polarized distribution of Bcr-Abl in migrating myeloid cells and co-localization of Bcr-Abl and its target proteins
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1165
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Paris A Skourides, Samanthi A Perera & Ruibao Ren
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Abstract Full Article PDF
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C-myc overexpression and p53 loss cooperate to promote genomic instability
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1177
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XiaoYing Yin, Linnette Grove, Nabanita S Datta, Michael W Long & Edward V Prochownik
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Abstract Full Article PDF
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Superimposed histologic and genetic mapping of chromosome 9 in progression of human urinary bladder neoplasia: implications for a genetic model of multistep urothelial carcinogenesis and early detection of urinary bladder cancer
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1185
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Bogdan Czerniak, Vijaya Chaturvedi, Li Li, Sherie Hodges, Dennis Johnston, Jae Y Ro, Rajyalakshmi Luthra, Christopher Logothetis, Andrew C Von Eschenbach, H Barton Grossman, William F Benedict & John G Batsakis
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Abstract Full Article PDF
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Level of retinoblastoma protein expression correlates with p16 (MTS-1/INK4A/CDKN2) status in bladder cancer
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1197
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William F Benedict, Seth P Lerner, Jain Zhou, Xiaohua Shen, Hideo Tokunaga & Bogdan Czerniak
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Abstract Full Article PDF
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Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma
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1205
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Jason Cook, Sumathi Krishnan, Subbian Ananth, Stephen F Sells, Yang Shi, McClellan M Walther, W Marston Linehan, Vikas P Sukhatme, Michael H Weinstein & Vivek M Rangnekar
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Abstract Full Article PDF
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TIF1 , a novel member of the transcriptional intermediary factor 1 family
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1209
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Letizia Venturini, Jun You, Michael Stadler, René Galien, Valérie Lallemand, Marcel HM Koken, Marie G Mattei, Arnold Ganser, Pierre Chambon, Régine Losson & Hugues de Thé
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Abstract Full Article PDF
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Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation
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1219
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Roger A Greenberg, Rónán C O'Hagan, Hongyu Deng, Qiurong Xiao, Steven R Hann, Robert R Adams, Serge Lichtsteiner, Lynda Chin, Gregg B Morin & Ronald A DePinho
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Abstract Full Article PDF
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Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530
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1227
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Cay Egan, Andrew Pang, Denise Durda, Heung-Chin Cheng, Jerry H Wang & Donald J Fujita
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Abstract Full Article PDF
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Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21
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1239
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Atsushi Suzuki, Yumi Tsutomi, Masayuki Miura & Kouichi Akahane
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Abstract Full Article PDF
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Short Reports
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Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability
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1245
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Kelli G Biden, Lisa A Simms, Margaret Cummings, Ron Buttenshaw, Estelle Schoch, Jeffrey Searle, Glenda Gobe, Jeremy R Jass, Stephen J Meltzer, Barbara A Leggett & Joanne Young
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Abstract Full Article PDF
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PKC acts as a growth and tumor suppressor in rat colonic epithelial cells
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1251
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Gian Paolo Perletti, Emanuela Marras, Paola Concari, Francesco Piccinini & Armen H Tashjian Jr
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Abstract Full Article PDF
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Accelerated accumulation of somatic mutations in mice deficient in the nucleotide excision repair gene XPA
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1257
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Heidi Giese, Martijn ET Dollé, Aram Hezel, Harry van Steeg & Jan Vijg
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Abstract Full Article PDF
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