Articles
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The activation loop in Lck regulates oncogenic potential by inhibiting basal kinase activity and restricting substrate specificity
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3961
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Lorraine E Laham, Nishit Mukhopadhyay & Thomas M Roberts
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Abstract Full Article PDF
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The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila
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3971
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Sam E Scanga, Laurent Ruel , Richard C Binari, Brian Snow, Vuk Stambolic, Denis Bouchard, Malte Peters, Batista Calvieri, Tak W Mak, James R Woodgett & Armen S Manoukian
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Abstract Full Article PDF
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Isolation and characterization of sixteen novel p53 response genes
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3978
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Corinne Kostic & Phillip H Shaw
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Abstract Full Article PDF
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Influence of the human endogenous retrovirus-like element HERV-E.PTN on the expression of growth factor pleiotrophin: a critical role of a retroviral Sp1-binding site
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3988
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Anke M Schulte, Claudius Malerczyk, Rafael Cabal-Manzano, Jason J Gajarsa, Heinz-Joachim List, Anna Tate Riegel & Anton Wellstein
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Abstract Full Article PDF
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Inhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by Signal-Regulatory Proteins (SIRPs)
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3999
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Chuan-jin Wu, Zhengjun Chen, Axel Ullrich, Mark I Greene & Donald M O'Rourke
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Abstract Full Article PDF
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High levels of phosphorylated c-Jun, Fra-1, Fra-2 and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model
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4011
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Vassilis Zoumpourlis, Paraskevi Papassava, Spyros Linardopoulos, David Gillespie, Allan Balmain & Alexandros Pintzas
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Abstract Full Article PDF
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Cell-cell adhesion-mediated tyrosine phosphorylation of nectin-2 , an immunoglobulin-like cell adhesion molecule at adherens junctions
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4022
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Mitsuhiro Kikyo, Takashi Matozaki, Atsuko Kodama, Hiroshi Kawabe, Hiroyuki Nakanishi & Yoshimi Takai
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Abstract Full Article PDF
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Quantitative determination of Rap 1 activation in cyclic nucleotide-treated HL-60 leukemic cells: lack of Rap 1 activation in variant cells
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4029
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Friederike C von Lintig, Renate B Pilz & Gerry R Boss
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Abstract Full Article PDF
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pRb and Cdk regulation by N-(4-hydroxyphenyl)retinamide
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4035
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Silvia Panigone, Silvana Debernardi, Yoichi Taya, Enrico Fontanella, Rita Airoldi & Domenico Delia
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Abstract Full Article PDF
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Conformational phenotype of p53 is linked to nuclear translocation
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4042
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Supriya V Gaitonde, Jayme R Riley, Dianhua Qiao & Jesse D Martinez
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Abstract Full Article PDF
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BRCA1 activation of the GADD45 promoter
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4050
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Shunqian Jin, Hongcheng Zhao, Feiyue Fan, Patricia Blanck, Wenhong Fan, Amy B Colchagie, Albert J Fornace Jr & Qimin Zhan
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Abstract Full Article PDF
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Short report
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The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk
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4058
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Miguel Garcia-Guzman, Elise Larsen & Kristiina Vuori
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Abstract Full Article PDF
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Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells
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4066
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Alice Arapshian, Yuvarani S Kuppumbatti & Rafael Mira-y-Lopez
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Abstract Full Article PDF
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General effect of Sam68 on Rev/Rex regulated expression of complex retroviruses
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4071
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Thipparthi R Reddy, Wei-dong Xu & Flossie Wong-Staal
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Abstract Full Article PDF
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Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumors
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4075
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Radoslawa Nowak, Krzysztof Sikora, Agnieszka Pitas, Iwona Skoneczna & Stanislaw J Chrapusta
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Abstract Full Article PDF
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Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation
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4079
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Suet Yi Leung, Siu Tsan Yuen, Tsun Leung Chan, Annie SY Chan, Judy WC Ho, Kedo Kwan, Yiu Wah Fan, Kwan Ngai Hung, Lap Ping Chung & Andrew H Wyllie
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Abstract Full Article PDF
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