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Articles
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IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects
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5303
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L Behrend, D M Milne, M Stöter, W Deppert, LE Campbell, DW Meek & U Knippschild
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| Abstract Full Article PDF
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Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells
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5314
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Charanjit Sandhu, Jeffrey Donovan, Nandita Bhattacharya, Martha Stampfer, Peter Worland & Joyce Slingerland
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| Abstract Full Article PDF
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A cancer modifier role for parathyroid hormone-related protein
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5324
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Giacomo Manenti, Bernard Peissel, Manuela Gariboldi, F Stefania Falvella, Daniela Zaffaroni, Biagino Allaria, Simonetta Pazzaglia, Simonetta Rebessi, Vincenzo Covelli, Anna Saran & Tommaso A Dragani
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| Abstract Full Article PDF
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Reduced latency but no increased brain tumor penetrance in mice with astrocyte specific expression of a human p53 mutant
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5329
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Michael A Klein, Daniela Rüedi, Michimasa Nozaki, Elizabeth W Dell, Annie-Claire Diserens, Walter Seelentag, Robert C Janzer, Adriano Aguzzi & Monika E Hegi
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| Abstract Full Article PDF
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Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model
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5338
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Jalila Adnane, Rosalind J Jackson, Santo V Nicosia, Alan B Cantor, W Jack Pledger & Sad M Sebti
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| Abstract Full Article PDF
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Regulation of a multigenic invasion programme by the transcription factor, AP-1: re-expression of a down-regulated gene, TSC-36, inhibits invasion
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5348
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Imogen MP Johnston, Heather J Spence, Joseph N Winnie, Lynn McGarry, J Keith Vass, Liam Meagher, Genevieve Stapleton & Bradford W Ozanne
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Adenovirus-mediated p16INK4a gene expression radiosensitizes non-small cell lung cancer cells in a p53-dependent manner
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5359
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Shinichiro Kawabe, Jack A Roth, Deborah R Wilson & Raymond E Meyn
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| Abstract Full Article PDF
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Oncogenic insertional mutations in the P-loop of Ras are overactive in MAP kinase signaling
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5367
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Boris Klockow, Mohammad R Ahmadian, Christoph Block & Alfred Wittinghofer
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| Abstract Full Article PDF
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Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development
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5377
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Agnès Gouble & Dominique Morello
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| Abstract Full Article PDF
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Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells
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5385
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Kevin Tri Nguyen, Wang-June Wang, Joseph L-K Chan & Lu-Hai Wang
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| Abstract Full Article PDF
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Chimeric VEGFRs are activated by a small-molecule dimerizer and mediate downstream signalling cascades in endothelial cells
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5398
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Emma L Knight, Andrea J Warner, Anthony Maxwell & Sally A Prigent
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| Abstract Full Article PDF
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MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells
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5406
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Motoyoshi Tanaka, Dimpy Koul, Michael A Davies, Monica Liebert, Peter A Steck & H Barton Grossman
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| Abstract Full Article PDF
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Short Report
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Loss of heterozygosity, allele silencing and decreased expression of p73 gene in breast cancers: Prevalence of alterations in inflammatory breast cancers
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5413
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JC Ahomadegbe, S Tourpin, M Kaghad, L Zelek, M Vayssade, MC Mathieu, F Rochard, M Spielmann, T Tursz, D Caput, G Riou & J Bénard
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