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British Journal of Pharmacology

14 August 1997, Volume 121, Issue 8
Table of Contents

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Evidence for the involvement of P2-purinoceptors in the cholinergic contraction of the guinea-pig ileum 1507
Loránd Barthó, László Lénárd, Jr. & Carlo A. Maggi
Abstract    Full Article (PDF)

Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries 1509
F. Plane, M. Holland, G.J. Waldron, C.J. Garland & J.P. Boyle
Abstract    Full Article (PDF)

Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents 1513
M.J. Field, R.J. Oles, A.S. Lewis, S. McCleary, J. Hughes & L. Singh
Abstract    Full Article (PDF)

Effects of beta2-agonist- and dexamethasone-treatment on relaxation and regulation of beta-adrenoceptors in human bronchi and lung tissue 1523
R.W. Hauck, M. Harth, C. Schulz, H. Präuer, M. Böhm & A. Schömig
Abstract    Full Article (PDF)

Effects of Ca2+ channel blocker neurotoxins on transmitter release and presynaptic currents at the mouse neuromuscular junction 1531
Eleonora Katz, Darío A. Protti, Pablo A. Ferro, Marcelo D. Rosato Siri & Osvaldo D. Uchitel
Abstract    Full Article (PDF)

Influence of metabotropic glutamate receptor agonists on the inhibitory effects of adenosine A1 receptor activation in the rat hippocampus 1541
Alexandre de Mendonça & J.A. Ribeiro
Abstract    Full Article (PDF)

Contribution of phosphodiesterase isozymes to the regulation of the L-type calcium current in human cardiac myocytes 1549
Katsuya Kajimoto, Nobuhisa Hagiwara, Hiroshi Kasanuki & Saichi Hosoda
Abstract    Full Article (PDF)

Inhibition by cannabinoid receptor agonists of acetylcholine release from the guinea-pig myenteric plexus 1557
Angela A. Coutts & Roger G. Pertwee
Abstract    Full Article (PDF)

Fluoroquinolone (ciprofloxacin) secretion by human intestinal epithelial (Caco-2) cells 1567
M.E. Cavet, M. West & N.L. Simmons
Abstract    Full Article (PDF)

Activation of microsomal cytochrome P450 mono-oxygenase by Ca2+ store depletion and its contribution to Ca2+ entry in porcine aortic endothelial cells 1579
Bernhard G. Hoebel, Gert M. Kostner & Wolfgang F. Graier
Abstract    Full Article (PDF)

Evidence that the substance P-induced enhancement of pacemaking in lymphatics of the guinea-pig mesentery occurs through endothelial release of thromboxane A2 1589
Sharyn E. Rayner & Dirk F. Van Helden
Abstract    Full Article (PDF)

Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and dogs 1597
Michael Mark & Wolfgang Grell
Abstract    Full Article (PDF)

NANC transmitters in the female pig urethra - localization and modulation of release via alpha2-adrenoceptors and potassium channels 1605
Viktoria Werkström, Katarina Persson & Karl-Erik Andersson
Abstract    Full Article (PDF)

Investigation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat 1613
Helen C. Jackson, M. Clair Bearham, Lisa J. Hutchins, Sarah E. Mazurkiewicz, Andrew M. Needham & David J. Heal
Abstract    Full Article (PDF)

Involvement of interleukin-1beta, nerve growth factor and prostaglandin E2 in endotoxin-induced localized inflammatory hyperalgesia 1619
Bared Safieh-Garabedian, Salim A. Kanaan, John J. Haddad, Pamela Abou Jaoude, Suhayl J. Jabbur & Nayef E. Saadé
Abstract    Full Article (PDF)

Study of the in vivo and in vitro cardiovascular effects of a hydralazine-like vasodilator agent (HPS-10) in normotensive rats 1627
Francisco Orallo
Abstract    Full Article (PDF)

Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat 1637
Teresa Iuvone, Nancy Van Osselaer, Fulvio D'Acquisto, Rosa Carnuccio & Arnold G. Herman
Abstract    Full Article (PDF)

Capsaicin and neurokinin A-induced bronchoconstriction in the anaesthetised guinea-pig: evidence for a direct action of menthol on isolated bronchial smooth muscle 1645
C.E. Wright, E.A. Laude, T.J. Grattan & A.H. Morice
Abstract    Full Article (PDF)

Induction of neutrophil chemotactic factor production by staurosporine in rat peritoneal neutrophils 1651
Takeo Edamatsu, Yi-Qun Xiao, Jun-ichi Tanabe, Suetsugu Mue & Kazuo Ohuchi
Abstract    Full Article (PDF)

Role of endothelin receptors, calcium and nitric oxide in the potentiation by endothelin-1 of the sympathetic contraction of rabbit ear artery during cooling 1659
A.L. García-Villalón, J. Padilla, N. Fernández, L. Monge, B. Gómez & G. Diéguez
Abstract    Full Article (PDF)

The role of cyclic nucleotides in guinea-pig bladder contractility 1665
Penelope A. Longhurst, Janice A.K. Briscoe, David J. Rosenberg & Robert E. Leggett
Abstract    Full Article (PDF)

Characterization of [3H]-prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virus 1673
Fiona H. Marshall, Kalpana Patel, Kenneth Lundstrom, Janet Camacho, Steven M. Foord & Melanie G. Lee
Abstract    Full Article (PDF)

Profile of SB-204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures 1679
Neil Upton, Tom P. Blackburn, Colin A. Campbell, Duncan Cooper, Martyn L. Evans, Hugh J. Herdon, Penny D. King, Alison M. Ray, Tania O. Stean, Wai N. Chan, John M. Evans & Mervyn Thompson
Abstract    Full Article (PDF)

Characterization of the binding of [3H]-SB-204269, a radiolabelled form of the new anticonvulsant SB-204269, to a novel binding site in rat brain membranes 1687
Hugh J. Herdon, Jeffrey C. Jerman, Tania O. Stean, Derek N. Middlemiss, Wai N. Chan, Antonio K. Vong, John M. Evans, Mervyn Thompson & Neil Upton
Abstract    Full Article (PDF)

Characterization of the signalling pathways involved in ATP and basic fibroblast growth factor-induced astrogliosis 1692
Chiara Bolego, Stefania Ceruti, Roberta Brambilla, Lina Puglisi, Flaminio Cattabeni, Geoffrey Burnstock & Maria P. Abbracchio
Abstract    Full Article (PDF)

Characterization of the Ca2+ responses evoked by ATP and other nucleotides in mammalian brain astrocytes 1700
Carlo Centemeri, Chiara Bolego, Maria P. Abbracchio, Flaminio Cattabeni, Lina Puglisi, Geoffrey Burnstock & Simonetta Nicosia
Abstract    Full Article (PDF)

Influence of AMPA/kainate receptors on extracellular 5-hydroxytryptamine in rat midbrain raphe and forebrain 1707
Rui Tao, Zhiyuan Ma & Sidney B. Auerbach
Abstract    Full Article (PDF)

Evidence that methyl arachidonyl fluorophosphonate is an irreversible cannabinoid receptor antagonist 1716
Susanthi R. Fernando & Roger G. Pertwee
Abstract    Full Article (PDF)

Characterization of alpha2-adrenoceptors mediating contraction of dog saphenous vein: identity with the human alpha2A subtype 1721
S.J. MacLennan, L.A. Luong, J.R. Jasper, Z.P. To & R.M. Eglen
Abstract    Full Article (PDF)

Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro 1730
Shigemi Yoshihara, Anders Lindén, Kazuhisa Kashimoto, Yumiko Nagano, Tohju Ichimura & Jay A. Nadel
Abstract    Full Article (PDF)

Carrier-dependent and Ca2+-dependent 5-HT and dopamine release induced by (+)-amphetamine, 3,4-methylendioxy-methamphetamine, p-chloroamphetamine and (+)-fenfluramine 1735
Daniela Crespi, Tiziana Mennini & Marco Gobbi
Abstract    Full Article (PDF)

ATP release and contraction mediated by different P2-receptor subtypes in guinea-pig ileal smooth muscle 1744
Katsuichi Matsuo, Takeshi Katsuragi, Sono Fujiki, Chiemi Sato & Tatsuo Furukawa
Abstract    Full Article (PDF)

Involvement of protein kinase C in the UTP-mediated potentiation of cyclic AMP accumulation in mouse J774 macrophages 1749
W.W. Lin & B.C. Chen
Abstract    Full Article (PDF)

Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat 1758
Helen C. Jackson, Andrew M. Needham, Lisa J. Hutchins, Sarah E. Mazurkiewicz & David J. Heal
Abstract    Full Article (PDF)

Regulation of bradykinin B2-receptor expression by oestrogen 1763
Paolo Madeddu, Costanza Emanueli, Maria Vittoria Varoni, Maria Piera Demontis, Vittorio Anania, Nicola Gorioso & Julie Chao
Abstract    Full Article (PDF)

Reduction of urinary 8-epi-prostaglandin F2alpha during cyclo-oxygenase inhibition in rats but not in man 1770
Angela Bachi, Raffaella Brambilla, Roberto Fanelli, Roberto Bianchi, Ettore Zuccato & Chiara Chiabrando
Abstract    Full Article (PDF)

Investigation into the contractile response of melatonin in the guinea-pig isolated proximal colon: the role of 5-HT4 and melatonin receptors 1775
A. Lucchelli, M.G. Santagostino-Barbone & M. Tonini
Abstract    Full Article (PDF)

The involvement of tumour necrosis factor-alpha in the protective effects of 17beta oestradiol in splanchnic ischaemia-reperfusion injury 1782
Francesco Squadrito, Domenica Altavilla, Giovanni Squadrito, Giuseppe M. Campo, Mariarita Arlotta, Vincenzo Arcoraci, Letteria Minutoli, Antonino Saitta & Achille P. Caputi
Abstract    Full Article (PDF)

Differential effects of lovastatin on mitogen induced calcium influx in human cultured vascular smooth muscle cells 1789
G.F. Clunn, J.S. Lymn, M. Schachter & A.D. Hughes
Abstract    Full Article (PDF)

Inhibitory effect of a new steroidal saponin, OSW-1, on ovarian functions in rats 1796
Kazuhiro Tamura, Hideo Honda, Yoshihiro Mimaki, Yutaka Sashida & Hiroshi Kogo
Abstract    Full Article (PDF)

Catecholamine modulatory effects of nepicastat (RS-25560-197), a novel, potent and selective inhibitor of dopamine-beta-hydroxylase 1803
William C. Stanley, Bin Li, Douglas W. Bonhaus, Lowell G. Johnson, Keiho Lee, Seth Porter, Keith Walker, Greg Martinez, Richard M. Eglen, Roger L. Whiting & Sharath S. Hegde
Abstract    Full Article (PDF)

The effects of neuroleptic and tricyclic compounds on BKCa channel activity in rat isolated cortical neurones 1810
K. Lee, F. McKenna, I.C.M. Rowe & M.L.J. Ashford
Abstract    Full Article (PDF)

Agonist and antagonist modulation of [35S]-GTPgammaS binding in transfected CHO cells expressing the neurotensin receptor 1817
Emmanuel Hermans, Muriel Geurts & Jean-Marie Maloteaux
Abstract    Full Article (PDF)

Intrarenal haemodynamics and renal dysfunction in endotoxaemia: effects of nitric oxide synthase inhibition 1824
Colin G.M. Millar & Christoph Thiemermann
Abstract    Full Article (PDF)

© Macmillan Publishers Ltd 1997

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