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British Journal of Pharmacology

September 1998, Volume 125, Issue 1
Table of Contents

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Special Report

Inhibition of the gap junctional component of endothelium-dependent relaxations in rabbit iliac artery by 18-alpha glycyrrhetinic acid 1
Hannah J. Taylor, Andrew T. Chaytor, W. Howard Evans & Tudor M. Griffith
Abstract    Full Article (PDF)

Original Articles

Somatostatin displayed on filamentous phage as a receptor-specific agonist 5
Mat Rousch, Jan T. Lutgerink, James Coote, Adriaan de Bruïne, Jan-Willem Arends & Hennie R. Hoogenboom
Abstract    Full Article (PDF)

ATP-sensitive K+ channels in smooth muscle cells of guinea-pig mesenteric lymphatics: role in nitric oxide and beta-adrenoceptor agonist-induced hyperpolarizations 17
Pierre-Yves von der Weid
Abstract    Full Article (PDF)

Investigation on the mechanisms involved in the central protective effect of amylin on gastric ulcers in rats 23
F. Guidobono, F. Pagani, C. Ticozzi, V. Sibilia & C. Netti
Abstract    Full Article (PDF)

Antithrombotic activity of a monoclonal antibody inducing the substrate form of plasminogen activator inhibitor type 1 in rat models of venous and arterial thrombosis 29
C.N. Berry, C. Lunven, I. Lechaire, C. Girardot & S.E. O'Connor
Abstract    Full Article (PDF)

Influence of various combinations of specific antibody dose and affinity on tissue imipramine redistribution 35
Corinne Ragusi, Gabrielle Boschi, Patricia Risède, Richard Rips, Kenneth Harrison & Jean-Michel Scherrmann
Abstract    Full Article (PDF)

Potent vasodilatory with minor cardiodepressant actions of mibefradil in human cardiac tissue 41
Klara Brixius, Valeska Mohr, Jochen Müller-Ehmsen, Susanne Hoischen, Götz Münch & Robert H.G. Schwinger
Abstract    Full Article (PDF)

The transport of the anti-HIV drug, 2',3'-didehydro-3'-deoxythymidine (D4T), across the blood-brain and blood-cerebrospinal fluid barriers 49
Sarah A. Thomas & Malcolm B. Segal
Abstract    Full Article (PDF)

Endothelin-1 stimulates sodium-dependent calcium efflux from bovine adrenal chromaffin cells in culture 55
Hitoshi Houchi, Masanori Yoshizumi, Koichiro Tsuchiya, Masao Hirose, Tetsuya Kitagawa, Toshihide Kujime, Eiji Shimizu, Yasuharu Niwa, Kazuo Minakuchi & Toshiaki Tamaki
Abstract    Full Article (PDF)

Effects of mitogen-activated protein kinase kinase inhibitor PD 098059 on antigen challenge of guinea-pig airways in vitro 61
F. Tsang, A.H.M. Koh, W.L. Ting, P.T.H. Wong & W.S.F. Wong
Abstract    Full Article (PDF)

5-Hydroxytryptamine receptors mediating vasoconstriction and vasodilation in perinatal and adult rabbit small pulmonary arteries 69
Ian Morecroft & Margaret R. MacLean
Abstract    Full Article (PDF)

Augmented myocardial ischaemia by nicotine - Mechanisms and their possible significance 79
Karsten Schrör, Katja C. Zimmermann & Roman Tannhäuser
Abstract    Full Article (PDF)

Peripheral and/or central effects of racemic-, S(+)- and R(-)-flurbiprofen on inflammatory nociceptive processes: a c-Fos protein study in the rat spinal cord 87
Jaroslava Buritova & Jean-Marie Besson
Abstract    Full Article (PDF)

Influence of aminoguanidine on parameters of liver injury and regeneration induced in rats by a necrogenic dose of thioacetamide 102
Carmen Díez-Fernández, Nuria Sanz, Alberto M. Alvarez, Asunción Zaragoza & María Cascales
Abstract    Full Article (PDF)

Human vascular to cardiac tissue selectivity of L- and T-type calcium channel antagonists 109
Doreen Sarsero, Toshimasa Fujiwara, Peter Molenaar & James A. Angus
Abstract    Full Article (PDF)

Differential effect of propofol on sympathetic neurotransmission in isolated human omental arteries and veins 120
Susanna M. Wallerstedt & Mikael Bodelsson
Abstract    Full Article (PDF)

Rilmenidine reveals differences in the pharmacological characteristics of prejunctional alpha2-adrenoceptors in the guinea-pig, rat and pig 127
A. Ali, H.-Y. Cheng, K.N. Ting & V.G. Wilson
Abstract    Full Article (PDF)

Effect of chronic hypoxia on adrenoceptor responses of ovine foetal umbilical vessels 136
Lubo Zhang, Xiangqun Hu & Lawrence D. Longo
Abstract    Full Article (PDF)

Kinin B2 receptor-mediated contraction of tail arteries from normal or streptozotocin-induced diabetic rats 143
Zunzhe Wang, Lingyun Wu & Rui Wang
Abstract    Full Article (PDF)

Inhibition of chemotaxis in A7r5 rat smooth muscle cells by a novel panel of inhibitors 152
B.A. Saxty,, M. Yadollahi-Farsani, P Kefalas, S. Paul & J. MacDermot
Abstract    Full Article (PDF)

Assessment of the effect of malaria infection on hepatic clearance of dihydroartemisinin using rat liver perfusions and microsomes 159
Kevin T. Batty, Kenneth F. Ilett, Geoffrey Edwards, Shane M. Powell, James L. Maggs, B. Kevin Park & Timothy M. E. Davis
Abstract    Full Article (PDF)

Involvement of barium-sensitive K+ channels in endothelium-dependent vasodilation produced by hypercapnia in rat mesenteric vascular beds 168
Kaoru Okazaki, Masayuki Endou & Fukuichiro Okumura
Abstract    Full Article (PDF)

Attenuation of tolerance to opioid-induced antinociception and protection against morphine-induced decrease of neurofilament proteins by idazoxan and other I2-imidazoline ligands 175
M. Assumpció Boronat, Gabriel Olmos & Jesús A. García-Sevilla
Abstract    Full Article (PDF)

Relaxant effects of L-citrulline in rabbit vascular smooth muscle 186
E. Ruiz & T. Tejerina
Abstract    Full Article (PDF)

Cytokine induction of NO synthase II in human DLD-1 cells: roles of the JAK-STAT, AP-1 and NF-B-signaling pathways 193
Hartmut Kleinert, Thomas Wallerath, Gerhard Fritz, Irmgard Ihrig-Biedert, Fernando Rodriguez-Pascual, David A. Geller & Ulrich Förstermann
Abstract    Full Article (PDF)

SB-224289 - a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity 202
J.V. Selkirk, C. Scott, M. Ho, M.J. Burton, J. Watson, L.M. Gaster, L. Collin, B.J. Jones, D.N. Middlemiss & G.W. Price
Abstract    Full Article (PDF)

Molecular cloning and functional characterization of a rat somatostatin sst2(b) receptor splice variant 209
Marcus Schindler, Emma J. Kidd, Alan M. Carruthers, Mark A. Wyatt, Emma M. Jarvie, Lynda A. Sellers, Wasyl Feniuk & Patrick P.A. Humphrey
Abstract    Full Article (PDF)

Catecholamine transport by the organic cation transporter type 1 (OCT1) 218
Tilo Breidert, Folker Spitzenberger, Dirk Gründemann & Edgar Schömig
Abstract    Full Article (PDF)

Evidence that S-adenosyl-L-methionine diastereoisomers may reduce ischaemia-reperfusion injury by interacting with purinoceptors in isolated rat liver 225
J. Bruce Dunne, Barry Alexander, Roger Williams & J. Michael Tredger
Abstract    Full Article (PDF)

© Macmillan Publishers Ltd 1998

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