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British Journal of Pharmacology

December 1998, Volume 125, Issue 7
Table of Contents

Journal Home
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Review Article

Orphan G-protein-coupled receptors: the next generation of drug targets? 1387
Shelagh Wilson, Derk J. Bergsma, Jon K. Chambers, Alison I. Muir, Kenneth G.M. Fantom, Catherine Ellis, Paul R. Murdock, Nicole C. Herrity & Jeffrey M. Stadel
Abstract    Full Article (PDF)

Special Report

In vitro functional evidence of neuronal cannabinoid CB1 receptors in human ileum 1393
Tiziano Croci, Luciano Manara, Giulio Aureggi, Fabio Guagnini, Murielle Rinaldi-Carmona, Jean-Pierre Maffrand, Gérard Le Fur, Sylvain Mukenge & Gianfranco Ferla
Abstract    Full Article (PDF)

Original Articles

Distribution of the perivascular nerve Ca2+ receptor in rat arteries 1397
Yanlin Wang & Richard D. Bukoski
Abstract    Full Article (PDF)

Stimulation of airway sensory nerves by cyclosporin A and FK506 in guinea-pig isolated bronchus 1405
S. Harrison, S. Reddy, C.P. Page & D. Spina
Abstract    Full Article (PDF)

Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT1 and 5-HT2 receptors 1413
J. Watson, S. Brough, M.C. Coldwell, T. Gager, M. Ho, A.J. Hunter, J. Jerman, D.N. Middlemiss, G.J. Riley & A.M. Brown
Abstract    Full Article (PDF)

Effects of depolarizing stimuli on calcium homeostasis in cultured rat motoneurones 1421
Jean-Pierre Hubert, Marie-Claude Burgevin, Faraj Terro, Jacques Hugon & Adam Doble
Abstract    Full Article (PDF)

Modulation of AT1 receptor-mediated contraction of rat uterine artery by AT2 receptors 1429
Adam S. Zwart, Elizabeth A. Davis & Robert E. Widdop
Abstract    Full Article (PDF)

Carbon monoxide is a major contributor to the regulation of vascular tone in aortas expressing high levels of haeme oxygenase-1 1437
Ivan A. Sammut, Roberta Foresti, James E. Clark, David J. Exon, Martin J.J. Vesely, Padmini Sarathchandra, Colin J. Green & Roberto Motterlini
Abstract    Full Article (PDF)

Endothelium-dependent contractile actions of proteinase-activated receptor-2-activating peptides in human umbilical vein: release of a contracting factor via a novel receptor 1445
Mahmoud Saifeddine, Samir S. Roy, Bahjat Al-Ani, Chris R. Triggle & Morley D. Hollenberg
Abstract    Full Article (PDF)

The role of nitric oxide and metalloproteinases in the pathogenesis of hyperoxia-induced lung injury in newborn rats 1455
Anna Radomski, Grzegorz Sawicki, David M. Olson & Marek W. Radomski
Abstract    Full Article (PDF)

Pharmacological characterization of the human vasopressin receptor subtypes stably expressed in Chinese hamster ovary cells 1463
Atsuo Tahara, Masayuki Saito, Toru Sugimoto, Yuichi Tomura, Koh-ichi Wada, Toshiyuki Kusayama, Junko Tsukada, Noe Ishii, Takeyuki Yatsu, Wataru Uchida & Akihiro Tanaka
Abstract    Full Article (PDF)

Effect of lercanidipine and its (R)-enantiomer on atherosclerotic lesions induced in hypercholesterolemic rabbits 1471
Maurizio R. Soma, Malvina Natali, Elena Donetti, Roberta Baetta, Pierluigi Farina, Amedeo Leonardi, Carmen Comparato, Laura Barberi & Alberico L. Catapano
Abstract    Full Article (PDF)

Desensitization of the histamine H1-receptor and transcriptional down-regulation of histamine H1-receptor gene expression in bovine tracheal smooth muscle 1477
J.L. Pype, J.C.W. Mak, L.J. Dupont, G.M. Verleden & P.J. Barnes
Abstract    Full Article (PDF)

Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships 1485
K. Varani, G. Calo', A. Rizzi, S. Merighi, G. Toth, R. Guerrini, S. Salvadori, P.A. Borea & D. Regoli
Abstract    Full Article (PDF)

Human mast cell chymase induces the accumulation of neutrophils, eosinophils and other inflammatory cells in vivo 1491
Shaoheng He & Andrew F. Walls
Abstract    Full Article (PDF)

Expression of cyclic GMP-inhibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: Differential subcellular localization and regulated expression by cyclic AMP 1501
H. Liu & D.H. Maurice
Abstract    Full Article (PDF)

Inhibition of ornithine decarboxylase potentiates nitric oxide production in LPS-activated J774 cells 1511
Anwar R. Baydoun & David M.L. Morgan
Abstract    Full Article (PDF)

Studies of the antagonist actions of (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid (ATPO) on non-NMDA receptors in cultured rat neurones 1517
W.-M. Dai, B. Ebert, U. Madsen & J.D.C. Lambert
Abstract    Full Article (PDF)

Pharmacological modulation of GABAA receptor-mediated postsynaptic potentials in the CA1 region of the rat hippocampus 1529
Nicholas A. Manuel & Ceri H. Davies
Abstract    Full Article (PDF)

The influence of antibodies to TNF-alpha and IL-1beta on haemodynamic responses to the cytokines, and to lipopolysaccharide, in conscious rats 1543
S.M. Gardiner, P.A. Kemp, J.E. March, J. Woolley & T. Bennett
Abstract    Full Article (PDF)

Inhibition by inorganic ions of a sustained calcium signal evoked by activation of mGlu5 receptors in rat cortical neurons and glia 1551
Larissa S. Prothero, Christopher D. Richards & Alistair Mathie
Abstract    Full Article (PDF)

Involvement of 5-HT6 receptors in nigro-striatal function in rodents 1562
Anne Bourson, Frank G. Boess, Michael Bös & Andrew J. Sleight
Abstract    Full Article (PDF)

Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with Delta-9-tetrahydrocannabinol 1567
Daniel M. Hutcheson, Eleni Th. Tzavara, Claire Smadja, Emmanuel Valjent, Bernard P. Roques, Jacques Hanoune & Rafael Maldonado
Abstract    Full Article (PDF)

Brain sites involved in the antinociceptive effect of bradykinin in rats 1578
L.B. Couto, F.M.A. Corrêa & I.R. Pelá
Abstract    Full Article (PDF)

Developmental changes in endothelium-dependent vasodilation and the influence of superoxide anions in perinatal rabbit pulmonary arteries 1585
Ian Morecroft & Margaret R. MacLean
Abstract    Full Article (PDF)

The effect of inhibitors of receptor internalization on the desensitization and resensitization of three Gs-coupled receptor responses 1594
Stuart J. Mundell & Eamonn Kelly
Abstract    Full Article (PDF)

Distinct PKC isoforms mediate the activation of cPLA2 and adenylyl cyclase by phorbol ester in RAW264.7 macrophages 1601
Wan-W. Lin & Bin C. Chen
Abstract    Full Article (PDF)

Modelling of the pharmacodynamic interaction between phenytoin and sodium valproate 1610
O.E. Della Paschoa, R.A. Voskuyl & M. Danhof
Abstract    Full Article (PDF)

Brain-to-blood partition and in vivo inhibition of 5-hydroxytryptamine reuptake and quipazine-mediated behaviour of nefazodone and its main active metabolites in rodents 1617
Angelo Nacca, Giovanna Guiso, Claudia Fracasso, Luigi Cervo & Silvio Caccia
Abstract    Full Article (PDF)

© Macmillan Publishers Ltd 1998

As part of one of the world's largest publishers, Stockton Press has a substantial list of leading international journals in the key areas of science and medicine. Specialist fields covered include: bone marrow transplantation, cell death and differentiation, critical care/intensive care, dentistry, dentomaxillofacial radiology, environmental epidemiology, gene therapy, hematology, human and experimental toxicology, exposure analysis, human hypertension, impotence research, industrial microbiology, industrial health, information systems, leukemia, lupus, microcirculation, molecular psychiatry, multiple sclerosis, neuroscience, nursing, nutrition, obesity, occupational medicine, oncology, oncology pharmacy practice, operations research, optometry and ophthalmology, oral diseases, orthopedics, paraplegia, perinatology, pharmacology, psychiatry, public health, spinal injury and disease.