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Editorial
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RNA repair as a novel to genetic therapy
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461
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BA Sullenger
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Perspective
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Politically correct gene therapy? A "clean environment" improves gene delivery to the brain!
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463
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PR Lowenstein, CE Thomas & MG Castro
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Papers
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Utilization of variant-type of human  -fetoprotein promoter in gene therapy targeting for hepatocellular carcinoma
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465
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H Ishikawa, K Nakata, F Mawatari, T Ueki, S Tsuruta, A Ido, K Nakao, Y Kato, N Ishii & K Eguchi
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| Abstract Full Article PDF
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Variation in the immune response to adenoviral vectors in the brain: influence of mouse strain, environmental conditions and priming
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471
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Y Ohmoto, MJA Wood, HM Charlton, K Kajiwara, VH Perry & KJ Wood
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| Abstract Full Article PDF
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Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer
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482
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D Lechardeur, K-J Sohn, M Haardt, PB Joshi, M Monck, RW Graham, B Beatty, J Squire, H O'Brodovich & GL Lukacs
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| Abstract Full Article PDF
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Murine MHC class II locus control region drives expression of human  -glucocerebrosidase in antigen presenting cells of transgenic mice
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498
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J Guy, R Willemsen, A Langeveld, F Grosveld & D Drabek
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| Abstract Full Article PDF
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Electropermeabilization of skeletal muscle enhances gene transfer in vivo
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508
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I Mathiesen
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Adenoviral reporter gene transfer to the human trabecular meshwork does not alter aqueous humor outflow. Relevance for potential gene therapy of glaucoma
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515
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T Borrás, LL Rowlette, SC Erzurum & DL Epstein
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| Abstract Full Article PDF
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Complete cure of established murine hepatocellular carcinoma is achievable by repeated injections of retroviruses carrying the herpes simplex virus thymidine kinase gene
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525
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S Kuriyama, K Masui, M Kikukawa, T Sakamoto, T Nakatani, S Nagao, M Yamazaki, H Yoshiji, H Tsujinoue, H Fukui, T Yoshimatsu & K Ikenaka
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| Abstract Full Article PDF
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The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium
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534
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C Kitson, B Angel, D Judd, S Rothery, NJ Severs, A Dewar, L Huang, SC Wadsworth, SH Cheng, DM Geddes & EWFW Alton
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| Abstract Full Article PDF
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Enhanced pancreatic tumor regression by a combination of adenovirus and retrovirus-mediated delivery of the herpes simplex virus thymidine kinase gene
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547
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M Carrió, A Romagosa, E Mercadé, A Mazo, M Nadal, A-M Gómez-Foix & C Fillat
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| Abstract Full Article PDF
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Adenoviral delivery of CTLA4Ig into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients
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554
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L Lu, A Gambotto, W-C Lee, S Qian, CA Bonham, PD Robbins & AW Thomson
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| Abstract Full Article PDF
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Hepatoma-specific antitumor activity of an albumin enhancer/promoter regulated herpes simplex virus in vivo
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564
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S-I Miyatake, S Tani, F Feigenbaum, P Sundaresan, H Toda, O Narumi, H Kikuchi, N Hashimoto, M Hangai, RL Martuza & SD Rabkin
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| Abstract Full Article PDF
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Macrophage inflammatory protein-2 gene therapy attenuates adenovirus- and acetaminophen-mediated hepatic injury
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573
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CM Hogaboam, KJ Simpson, SW Chensue, ML Steinhauser, NW Lukacs, J Gauldie, RM Strieter & SL Kunkel
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| Abstract Full Article PDF
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Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection
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585
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S Li, W-C Tseng, D Beer Stolz, S-P Wu, SC Watkins & L Huang
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| Abstract Full Article PDF
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PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
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595
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M Ogris, S Brunner, S Schüller, R Kircheis & E Wagner
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| Abstract Full Article PDF
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Transfer of the murine interleukin-12 gene in vivo by a Semliki Forest virus vector induces B16 tumor regression through inhibition of tumor blood vessel formation monitored by Doppler ultrasonography
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606
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C Asselin-Paturel, N Lassau, J-M Guinebretière, J Zhang, F Gay, F Bex, S Hallez, J Leclere, P Peronneau, F Mami-Chouaib & S Chouaib
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| Abstract Full Article PDF
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Design of a muscle cell-specific expression vector utilising human vascular smooth muscle -actin regulatory elements
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616
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M-C Keogh, D Chen, JF Schmitt, U Dennehy, VV Kakkar & NR Lemoine
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| Abstract Full Article PDF
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Co-delivery of T helper 1-biasing cytokine genes enhances the efficacy of gene gun immunization of mice: studies with the model tumor antigen -galactosidase and the BALB/c Meth A p53 tumor-specific antigen
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629
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T Tüting, A Gambotto, PD Robbins, WJ Storkus & AB DeLeo
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| Abstract Full Article PDF
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Inhibition of adenovirus-mediated gene transfer by bronchoalveolar lavage fluid
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637
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A Bastian & B Bewig
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Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery
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643
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PR Dash, ML Read, LB Barrett, MA Wolfert & LW Seymour
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| Abstract Full Article PDF
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Lipoplex size is a major determinant of in vitro lipofection efficiency
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651
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PC Ross & SW Hui
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| Abstract Full Article PDF
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Inhibition of HIV-1 by an anti-integrase single-chain variable fragment (SFv): delivery by SV40 provides durable protection against HIV-1 and does not require selection
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660
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M BouHamdan, L-X Duan, RJ Pomerantz & DS Strayer
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| Abstract Full Article PDF
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Efficient CFTR expression from AAV vectors packaged with promoters – the second generation
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667
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D Wang, H Fischer, L Zhang, P Fan, RX Ding & J Dong
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| Abstract Full Article PDF
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Enhancement of calcium phosphate-mediated transfection by inclusion of adenovirus in coprecipitates
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676
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JH Lee & MJ Welsh
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| Abstract Full Article PDF
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Brief Communications
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Gene delivery to the myocardium by intrapericardial injection
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683
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Y Fromes, A Salmon, X Wang, H Collin, A Rouche, A Hagège, K Schwartz & MY Fiszman
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| Abstract Full Article PDF
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In vivo targeted gene transfer into liver cells mediated by a novel galactosyl-D-lysine/D-serine copolymer
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689
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S Hisayasu, M Miyauchi, K Akiyama, T Gotoh, S Satoh & T Shimada
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| Abstract Full Article PDF
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Antigen-specific membrane fusion mediated by the haemagglutinin protein of influenza A virus: separation of attachment and fusion functions on different molecules
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694
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SM Patterson, R Swainsbury & EG Routledge
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| Abstract Full Article PDF
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5-Azacytidine prevents transgene methylation in vivo
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703
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M Di Ianni, A Terenzi, K Perruccio, R Ciurnelli, F Lucheroni, R Benedetti, MF Martelli & A Tabilio
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| Abstract Full Article PDF
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