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Editorial
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Who's afraid of replication-competent adenoviruses?
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709
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FJ Fallaux, AJ van der Eb & RC Hoeben
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| Full Article PDF
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Perspective
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Apoptin: nuclear switch triggers cancer cell death
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713
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Dr AL Murphy
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| Full Article PDF
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Papers
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Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system
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715
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L-J Chang, V Urlacher, T Iwakuma, Y Cui & J Zucali
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| Abstract Full Article PDF
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Rapid clearance of syngeneic transplanted hepatocytes following transduction with E-1-deleted adenovirus indicates early host immune responses and offers novel ways for studying viral vector, target cell and host interactions
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729
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S Gagandeep, M Ott, RP Sokhi & S Gupta
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| Abstract Full Article PDF
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Needle injection catheter delivery of the gene for an antibacterial agent inhibits neointimal formation
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737
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S Nikol, TY Huehns, E Krausz, S Armeanu, MG Engelmann, D Winder, B Salmons & B Hoefling
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| Abstract Full Article PDF
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Transient cyclophosphamide treatment before intraportal readministration of an adenoviral vector can induce re-expression of the original gene construct in rat liver
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749
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S Kuriyama, K Tominaga, M Kikukawa, T Tsujimoto, T Nakatani, H Tsujinoue, H Okuda, S Nagao, A Mitoro, H Yoshiji & H Fukui
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| Abstract Full Article PDF
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Adenovirus-mediated delivery of the Gax transcription factor to rat carotid arteries inhibits smooth muscle proliferation and induces apoptosis
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758
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H Perlman, Z Luo, K Krasinski, A Le Roux, A Mahfoudi, RC Smith, D Branellec & K Walsh
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| Abstract Full Article PDF
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Nitroreductase-mediated cell ablation is very rapid and mediated by a p53-independent apoptotic pathway
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764
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W Cui, B Gusterson & AJ Clark
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| Abstract Full Article PDF
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Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein
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771
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GJ Prud'homme & Y Chang
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| Abstract Full Article PDF
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Induction of tumor immunity by autologous B lymphoma cells expressing a genetically engineered idiotype
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778
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M Selmayr, J Strehl, J-P Kremer, E Kremmer, A Doenecke, M Hallek, H Menzel, K Thielemans, S Thierfelder & R Mocikat
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| Abstract Full Article PDF
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Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals
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785
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DC MacLaren, SS Gambhir, N Satyamurthy, JR Barrio, S Sharfstein, T Toyokuni, L Wu, AJ Berk, SR Cherry, ME Phelps & HR Herschman
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| Abstract Full Article PDF
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Myoblast transplantations lead to the expression of the laminin  2 chain in normal and dystrophic (dy/dy) mouse muscles
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792
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J-T Vilquin, B Guérette, J Puymirat, D Yaffe, FMS Tomé, M Fardeau, M Fiszman, K Schwartz & JP Tremblay
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| Abstract Full Article PDF
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Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectin
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801
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OA Harari, TJ Wickham, CJ Stocker, I Kovesdi, DM Segal, TY Huehns, C Sarraf & DO Haskard
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| Abstract Full Article PDF
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Potent antitumor effects mediated by local expression of the mature form of the interferon- inducing factor, interleukin-18 (IL-18)
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808
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T Osaki, W Hashimoto, A Gambotto, H Okamura, PD Robbins, M Kurimoto, MT Lotze & H Tahara
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| Abstract Full Article PDF
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Allograft transduction of IL-10 prolongs survival following orthotopic liver transplantation
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816
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K Shinozaki, H Yahata, H Tanji, T Sakaguchi, H Ito & K Dohi
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| Abstract Full Article PDF
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Gene transfer mediated by fusion protein hemagglutinin reconstituted in cationic lipid vesicles
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823
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P Schoen, A Chonn, PR Cullis, J Wilschut & P Scherrer
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| Abstract Full Article PDF
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Intratumoral delivery of IL-12 gene by polyvinyl polymeric vector system to murine renal and colon carcinoma results in potent antitumor immunity
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833
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SK Mendiratta, A Quezada, M Matar, J Wang, HL Hebel, S Long, JL Nordstrom & F Pericle
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| Abstract Full Article PDF
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Sustained gene expression in transplanted skin fibroblasts in rats
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840
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MQ Wei, DV Lejnieks, N Ramesh, S Lau, J Seppen & WRA Osborne
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| Abstract Full Article PDF
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Human PBMC-derived dendritic cells transduced with an adenovirus vector induce cytotoxic T-lymphocyte responses against a vector-encoded antigen in vitro
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845
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J Diao, JA Smythe, C Smyth, PB Rowe & IE Alexander
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| Abstract Full Article PDF
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Adenovirus-mediated tissue-targeted expression of the HSVtk gene for the treatment of breast cancer
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854
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LM Anderson, S Swaminathan, I Zackon, A-K Tajuddin, B Thimmapaya & SA Weitzman
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| Abstract Full Article PDF
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Cytotoxic T lymphocyte response against non-immunoselected tumor antigens predicts the outcome of gene therapy with IL-12-transduced tumor cell vaccine
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865
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M Rodolfo, C Zilocchi, B Cappetti, G Parmiani, C Melani & MP Colombo
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| Abstract Full Article PDF
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Photodynamic treatment of adenoviral vectors with visible light: an easy and convenient method for viral inactivation
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873
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FHE Schagen, ACE Moor, SC Cheong, SJ Cramer, H van Ormondt, AJ van der Eb, TMAR Dubbelman & RC Hoeben
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| Abstract Full Article PDF
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Specific tumor-cell killing with adenovirus vectors containing the apoptin gene
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882
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AM Pietersen, MM van der Eb, HJ Rademaker, DJM van den Wollenberg, MJWE Rabelink, PJK Kuppen, JH van Dierendonck, H van Ormondt, D Masman, CJH van de Velde, AJ van der Eb, RC Hoeben & MHM Noteborn
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| Abstract Full Article PDF
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CpG DNA and LPS induce distinct patterns of activation in human monocytes
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893
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G Hartmann & AM Krieg
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| Abstract Full Article PDF
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Replication-defective herpes simplex virus vectors for neurotrophic factor gene transfer in vitro and in vivo
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904
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P Marconi, M Simonato, S Zucchini, G Bregola, R Argnani, D Krisky, JC Glorioso & R Manservigi
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| Abstract Full Article PDF
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Targeted RNases: a feasibility study for use in HIV gene therapy
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913
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S Singwi, A Ramezani, SF Ding & S Joshi
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| Abstract Full Article PDF
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Allele replacement: an application that permits rapid manipulation of herpes simplex virus type 1 genomes
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922
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BC Horsburgh, MM Hubinette, D Qiang, MLE MacDonald & F Tufaro
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| Abstract Full Article PDF
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Transgene expression, but not gene delivery, is improved by adhesion-assisted lipofection of hematopoietic cells
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931
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H Keller, C Yunxu, G Marit, M Pla, J Reiffers, J Thèze & P Froussard
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| Abstract Full Article PDF
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Brief Communications
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Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium
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939
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T Hudde, SA Rayner, RM Comer, M Weber, JD Isaacs, H Waldmann, DFP Larkin & AJT George
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| Abstract Full Article PDF
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Hematopoietic cytokine-inducible gene expression from retroviral vectors
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944
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RL Saylors, KC Stine & J Derrick
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| Abstract Full Article PDF
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Suppression of HIV-1 transcription and replication by a Vpr mutant
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947
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BE Sawaya, K Khalili, J Rappaport, D Serio, W Chen, A Srinivasan & S Amini
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| Abstract Full Article PDF
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