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British Journal of Pharmacology

August 1999, Volume 128, Issue 1
Table of Contents

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Special Report

Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR 1
D. Smart, J. C. Jerman, S. J. Brough, S. L. Rushton, P. R. Murdock, F. Jewitt, N. A. Elshourbagy, C. E. Ellis, D. N. Middlemiss & F. Brown
Abstract    Full Article (PDF)

Papers

Enhancement by galactosamine of lipopolysaccharide(LPS)-induced tumour necrosis factor production and lethality: its suppression by LPS pretreatment 5
Yasuo Endo, Masahiko Shibazaki, Kouji Yamaguchi, Kenzou Kai, Shunji Sugawara, Haruhiko Takada, Hideaki Kikuchi & Katsuo Kumagai
Abstract    Full Article (PDF)

Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells 13
R. H.P. Porter, K. R. Benwell, H. Lamb, C. S. Malcolm, N. H. Allen, D. F. Revell, D. R. Adams & M. J. Sheardown
Abstract    Full Article (PDF)

Modulation by fluoxetine of striatal dopamine release following Delta9-tetrahydrocannabinol: a microdialysis study in conscious rats 21
Daniel T. Malone & David A. Taylor
Abstract    Full Article (PDF)

Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypes 27
Miriam Meyer, Franz Chudziak, Christina Schwanstecher, Mathias Schwanstecher & Uwe Panten
Abstract    Full Article (PDF)

Sulphonic acid derivatives as probes of pore properties of volume-regulated anion channels in endothelial cells 35
Guy Droogmans, Chantal Maertens, Jean Prenen & Bernd Nilius
Abstract    Full Article (PDF)

Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart 41
András Farkas, Aasim Qureshi & Michael J. Curtis
Abstract    Full Article (PDF)

Recovery of dopamine neuronal transporter but lack of change of its mRNA in substantia nigra after inactivation by a new irreversible inhibitor characterized in vitro and ex vivo in the rat 51
Jean-Claude Do Régo, Maria Syringas, Bertrand Leblond, Jean Costentin & Jean-Jacques Bonnet
Abstract    Full Article (PDF)

Rat chromaffin cells lack P2X receptors while those of the guinea-pig express a P2X receptor with novel pharmacology 61
M. Liu, P. M. Dunn, B. F. King & G. Burnstock
Abstract    Full Article (PDF)

Beta 3-adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium-derived nitric oxide in rat thoracic aorta 69
Jean-Noël Trochu, Véronique Leblais, Yohann Rautureau, Fabrizio Bévérelli, Hervé Le Marec, Alain Berdeaux & Chantal Gauthier
Abstract    Full Article (PDF)

Stereoselective interaction of thiopentone enantiomers with the GABAA receptor 77
D. J. Cordato, M. Chebib, L. E. Mather, G. K. Herkes & G. A.R. Johnston
Abstract    Full Article (PDF)

Electroencephalographic effects of thiopentone and its enantiomers in the rat: correlation with drug tissue distribution 83
Laurence E. Mather, Stephen R. Edwards & Colin C. Duke
Abstract    Full Article (PDF)

Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs 92
Ursula Eckstein-Ludwig, Jian Fei & Wolfgang Schwarz
Abstract    Full Article (PDF)

[Phe1(CH2-NH)Gly2]nociceptin-(1 - 13)-NH2 activation of an inward rectifier as a partial agonist of ORL1 receptors in rat periaqueductal gray 103
Lih-Chu Chiou
Abstract    Full Article (PDF)

Inhibition of heterologously expressed cystic fibrosis transmembrane conductance regulator Cl- channels by non-sulphonylurea hypoglycaemic agents 108
Z. Cai, K. A. Lansdell & D. N. Sheppard
Abstract    Full Article (PDF)

Inhibitory effect of nociceptin on [3H]-5-HT release from rat cerebral cortex slices 119
Anna Siniscalchi, Donata Rodi, Lorenzo Beani & Clementina Bianchi
Abstract    Full Article (PDF)

Endothelium-derived hyperpolarizing factor but not NO reduces smooth muscle Ca2+ during acetylcholine-induced dilation of microvessels 124
Steffen-Sebastian Bolz, Cor de Wit & Ulrich Pohl
Abstract    Full Article (PDF)

Selective beta1-adrenoceptor blockade enhances the activity of the stimulatory G-protein in human atrial myocardium 135
Tao Wang, Christopher Plumpton & Morris J. Brown
Abstract    Full Article (PDF)

Inhibition of quantal release from motor nerve by wortmannin 142
S. J. Hong & C. C. Chang
Abstract    Full Article (PDF)

trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets 149
Yuliya Dobrydneva, Roy L. Williams & Peter F Blackmore
Abstract    Full Article (PDF)

5-CT stimulation of adenylyl cyclase activity in guinea-pig hippocampus: evidence for involvement of 5-HT7 and 5-HT1A receptors 158
David R. Thomas, Derek N. Middlemiss, Stephen G. Taylor, Paul Nelson & Anthony M. Brown
Abstract    Full Article (PDF)

A new experimental approach in endothelium-dependent pharmacological investigations on isolated porcine coronary arteries mounted for impedance planimetry 165
László B. Tankó, Erich O. Mikkelsen & Ulf Simonsen
Abstract    Full Article (PDF)

Electrochemical and electrophysiological characterization of neurotransmitter release from sympathetic nerves supplying rat mesenteric arteries 174
William R. Dunn, James A. Brock & Todd A. Hardy
Abstract    Full Article (PDF)

Hepatocyte growth factor regulates human trophoblast motility and invasion: a role for nitric oxide 181
Judith E. Cartwright, Desmond P. Holden & Guy St. J. Whitley
Abstract    Full Article (PDF)

Modulatory effects of adenosine on inhibitory postsynaptic potentials in the lateral amygdala of the rat 190
Thomas Heinbockel & Hans-Christian Pape
Abstract    Full Article (PDF)

Alteration of glycogen and glucose metabolism in ischaemic and post-ischaemic working rat hearts by adenosine A1 receptor stimulation 197
Heather Fraser, Gary D. Lopaschuk & Alexander S. Clanachan
Abstract    Full Article (PDF)

Effects of C-type natriuretic peptide on rat cardiac contractility 206
Jean-Marie Brusq, Eric Mayoux, Laurent Guigui & Jorge Kirilovsky
Abstract    Full Article (PDF)

Pharmacological and molecular evidence for kinin B1 receptor expression in urinary bladder of cyclophosphamide-treated rats 213
P. Belichard, J. M. Luccarini, E. Defrêne, P. Faye, R. M. Franck, H. Duclos, J. L. Paquet & D. Pruneau
Abstract    Full Article (PDF)

Involvement of phospholipid signal transduction pathways in morphine tolerance in mice 220
Forrest L. Smith, Alka B. Lohmann & William L. Dewey
Abstract    Full Article (PDF)

Differential sensitivity of normal and cystic fibrosis airway epithelial cells to epinephrine 227
Kaarin K. Goncz, Luz Feeney & Dieter C. Gruenert
Abstract    Full Article (PDF)

Interleukin-1beta (IL-1beta) inhibition: a possible mechanism for the anti-inflammatory potency of liposomally conjugated methotrexate formulations in arthritis 234
A. S. Williams, S. G. Jones, R. M. Goodfellow, N. Amos & B. D. Williams
Abstract    Full Article (PDF)

Stimulation of bradykinin B2-receptors on endothelial cells induces relaxation and contraction in porcine basilar artery in vitro 241
Atsushi Miyamoto, , Shigeru Ishiguro & Akira Nishio
Abstract    Full Article (PDF)

Potent depression of stimulus evoked field potential responses in the medial entorhinal cortex by serotonin 248
Dietmar Schmitz, Tengis Gloveli, Ruth M. Empson & Uwe Heinemann
Abstract    Full Article (PDF)

The influence of allopurinol on kidney haemodynamic and excretory responses to renal ischaemia in anaesthetized rats 255
Dominique Hestin & Edward J. Johns
Abstract    Full Article (PDF)

Multiple calcium channels regulate neurotransmitter release from vagus nerve terminals in the cat bronchiole 262
Kanichiro Fujisawa, Hitoshi Onoue, Kihachiro Abe & Yushi Ito
Abstract    Full Article (PDF)

© Macmillan Publishers Ltd 1999

As part of one of the world's largest publishers, Stockton Press has a substantial list of leading international journals in the key areas of science and medicine. Specialist fields covered include: bone marrow transplantation, cell death and differentiation, critical care/intensive care, dentistry, dentomaxillofacial radiology, environmental epidemiology, gene therapy, hematology, human and experimental toxicology, exposure analysis, human hypertension, impotence research, industrial microbiology, industrial health, information systems, leukemia, lupus, microcirculation, molecular psychiatry, multiple sclerosis, neuroscience, nursing, nutrition, obesity, occupational medicine, oncology, oncology pharmacy practice, operations research, optometry and ophthalmology, oral diseases, orthopedics, paraplegia, perinatology, pharmacology, psychiatry, public health, spinal injury and disease.