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British Journal of Pharmacology

September 1999, Volume 128, Issue 2
Table of Contents

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Special Reports

Pro-oxidant challenge in vivo provokes the onset of NIDDM in the insulin resistant obese Zucker rat 269
David W. Laight, Kaushik M. Desai, Nitin K. Gopaul, Erik E. Änggård & Martin J. Carrier
Abstract    Full Article (PDF)

Ser203 as well as Ser204 and Ser207 in fifth transmembrane domain of the human beta2-adrenoceptor contributes to agonist binding and receptor activation 272
Takayuki Sato, Hiroyuki Kobayashi, Taku Nagao & Hitoshi Kurose
Abstract    Full Article (PDF)

Papers

Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des-Arg9bradykinin-induced coronary vasodilation 275
Peter G. McLean, Mauro Perretti & Amrita Ahluwalia
Abstract    Full Article (PDF)

Receptors mediating CGRP-induced relaxation in the rat isolated thoracic aorta and porcine isolated coronary artery differentiated by halpha CGRP8 - 37 283
F. M. Wisskirchen, D. W. Gray & I Marshall
Abstract    Full Article (PDF)

P2Y2 receptor-mediated inhibition of ion transport in distal lung epithelial cells 293
S. J. Ramminger, A. Collett, D. L. Baines, H. Murphie, H. L. McAlroy, R. E. Olver, S. K. Inglis & S. M. Wilson
Abstract    Full Article (PDF)

Block of gating currents related to K+ channels as a mechanism of action of clofilium and d-sotalol in isolated guinea-pig ventricular heart cells 301
Claire O Malécot & Jorge A Argibay
Abstract    Full Article (PDF)

Different receptors mediating the inhibitory action of exogenous ATP and endogenously released purines on guinea-pig intestinal peristalsis 313
Ákos Heinemann, Anaid Shahbazian, Loránd Barthó & Peter Holzer
Abstract    Full Article (PDF)

Cloning and preliminary pharmacological characterization of the anaphylatoxin C5a receptor in the rabbit 321
Dimcho R. Bachvarov, Steeve Houle, Magdalena Bachvarova, Johanne Bouthillier, Serge A. St-Pierre, Yoshihiro Fukuoka, Julia A. Ember & François Marceau
Abstract    Full Article (PDF)

Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis 327
Micaela M. Bernareggi, Maria G. Belvisi, Hema Patel, Peter J. Barnes & Mark A. Giembycz
Abstract    Full Article (PDF)

Cyclosporin A and tacrolimus (FK506) suppress expression of inducible nitric oxide synthase in vitro by different mechanisms 337
Gregory J. Dusting, Kazuhiro Akita, Haruyo Hickey, Melanie Smith & Vladimir Gurevich
Abstract    Full Article (PDF)

Nepalolide A inhibits the expression of inducible nitric oxide synthase by modulating the degradation of IB-alpha and IB-beta in C6 glioma cells and rat primary astrocytes 345
Chuen-Neu Wang, Young-Ji Shiao, Yun-Lian Lin & Chieh-Fu Chen
Abstract    Full Article (PDF)

Prevention of the expression of inducible nitric oxide synthase by a novel positive inotropic agent, YS 49, in rat vascular smooth muscle and RAW 264.7 macrophages 357
Young Jin Kang, Eui Bon Koo, Young Soo Lee, Hye Sook Yun-Choi & Ki Churl Chang
Abstract    Full Article (PDF)

Effect of hypoxia alone or combined with inflammation and 3-methylcholanthrene on hepatic cytochrome P450 in conscious rabbits 365
J. Kurdi, H. Maurice, A.O.S. El-Kadi, H. Ong, S. Dalkara, P. M. Bélanger & P. du Souich
Abstract    Full Article (PDF)

21-Aminosteroids prevent the down-regulation of hepatic cytochrome P450 induced by hypoxia and inflammation in conscious rabbits 374
Ahmed Galal & Patrick du Souich
Abstract    Full Article (PDF)

Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages 380
B. Y. Kang, Y. J. Song, K.-M. Kim, Y. K. Choe, S. Y. Hwang & T. S. Kim
Abstract    Full Article (PDF)

The effect of body temperature on myocardial protection conferred by ischaemic preconditioning or the selective adenosine A1 receptor agonist GR79236, in an anaesthetized rabbit model of myocardial ischaemia and reperfusion 385
A. Sheldrick, K. M. Gray, G. M. Drew & J. B. Louttit
Abstract    Full Article (PDF)

Functional expression of a cDNA encoding a human ecto-ATPase 396
Jesús Mateo, T. Kendall Harden & José L. Boyer
Abstract    Full Article (PDF)

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein 403
Catherine Martin, Georgina Berridge, Prakash Mistry, Christopher Higgins, Peter Charlton & Richard Callaghan
Abstract    Full Article (PDF)

Monophosphoryl lipid A provides biphasic cardioprotection against ischaemia-reperfusion injury in rat hearts 412
Nobushige Yamashita, Shiro Hoshida, Kinya Otsu, Naoyuki Taniguchi, Tsunehiko Kuzuya & Masatsugu Hori
Abstract    Full Article (PDF)

Long-term deprivation of oestrogens by ovariectomy potentiates beta-amyloid-induced working memory deficits in rats 419
Kiyofumi Yamada, Tomoko Tanaka, Li-Bo Zou, Kouji Senzaki, Kohji Yano, Takashi Osada, Olariu Ana, Xiuhai Ren, Tsutomu Kameyama & Toshitaka Nabeshima
Abstract    Full Article (PDF)

Resiniferatoxin-type phorboid vanilloids display capsaicin-like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1 428
A. Szallasi, T. Szabó, T. Bíró, S. Modarres, P. M. Blumberg, J. E. Krause, D. N. Cortright & G. Appendino
Abstract    Full Article (PDF)

Influence of redox compounds on nitrovasodilator-induced relaxations of rat coronary arteries 435
Michael E. Murphy
Abstract    Full Article (PDF)

Inhibition of the human ether-a-go-go-related gene (HERG) potassium channel by cisapride: affinity for open and inactivated states 444
B. D. Walker, C. B. Singleton, J. A. Bursill, K. R. Wyse, S. M. Valenzuela, M. R. Qiu, S. N. Breit & T. J. Campbell
Abstract    Full Article (PDF)

Iodinated radiographic contrast media inhibit shear stress- and agonist-evoked release of NO by the endothelium 451
I. R. Hutcheson, T. M. Griffith, M. R. Pitman, R. Towart, M. Gregersen, Helge Refsum & J. O.G. Karlsson
Abstract    Full Article (PDF)

Characterization of non-adrenergic, non-cholinergic inhibitory responses of the isolated guinea-pig trachea: differences between pre- and post-ganglionic nerve stimulation 458
James D. Moffatt, Bryan Dumsday & John R. McLean
Abstract    Full Article (PDF)

Regulation of cyclic AMP by extracellular ATP in cultured brain capillary endothelial cells 465
Zubeya Anwar, Jennifer L Albert, Sharon E Gubby, John P Boyle, Jonathon A Roberts, Tania E Webb & Michael R Boarder
Abstract    Full Article (PDF)

The effects of endomorphin-1 and endomorphin-2 in CHO cells expressing recombinant µ-opioid receptors and SH-SY5Y cells 472
C Harrison, S McNulty, D Smart, D J Rowbotham, D K Grandy, L A Devi & D G Lambert
Abstract    Full Article (PDF)

Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline 479
Anja G Teschemacher, Elizabeth P Seward, Jules C Hancox & Harry J Witchel
Abstract    Full Article (PDF)

Modulatory activity of extracellular H+ and Zn2+ on ATP-responses at rP2X1 and rP2X3 receptors 486
S S Wildman, B F King & G Burnstock
Abstract    Full Article (PDF)

L-NAME inhibits Mg2+-induced rat aortic relaxation in the absence of endothelium 493
Rapti Das, Gennadi M Kravtsov, Heather J Ballard & Chiu-Yin Kwan
Abstract    Full Article (PDF)

© Macmillan Publishers Ltd 1999

As part of one of the world's largest publishers, Stockton Press has a substantial list of leading international journals in the key areas of science and medicine. Specialist fields covered include: bone marrow transplantation, cell death and differentiation, critical care/intensive care, dentistry, dentomaxillofacial radiology, environmental epidemiology, gene therapy, hematology, human and experimental toxicology, exposure analysis, human hypertension, impotence research, industrial microbiology, industrial health, information systems, leukemia, lupus, microcirculation, molecular psychiatry, multiple sclerosis, neuroscience, nursing, nutrition, obesity, occupational medicine, oncology, oncology pharmacy practice, operations research, optometry and ophthalmology, oral diseases, orthopedics, paraplegia, perinatology, pharmacology, psychiatry, public health, spinal injury and disease.